Comorbidities in Patients with Psoriasis

被引:155
作者
Gottlieb, Alice B. [1 ]
Dann, Frank [2 ]
机构
[1] Tufts Med Ctr, Boston, MA 02111 USA
[2] VA Med Ctr, Long Beach, CA USA
关键词
Cardiovascular disease; Metabolic syndrome; Psoriasis; Psoriatic arthritis comorbidities; C-REACTIVE PROTEIN; CARDIOVASCULAR RISK-FACTORS; NECROSIS-FACTOR-ALPHA; RHEUMATOID-ARTHRITIS; METABOLIC SYNDROME; MYOCARDIAL-INFARCTION; CLINICAL-FEATURES; VASCULAR-DISEASES; MALIGNANT-TUMORS; LIPID PROFILE;
D O I
10.1016/j.amjmed.2009.06.021
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Psoriasis is a common chronic inflammatory disease that is associated with serious comorbidities, including psoriatic arthritis, reduced quality of life, depression, malignancy, and cardiovascular comorbidities. Patients with psoriasis have been shown to have an increased incidence of metabolic syndrome and cardiovascular disease compared with the general population. The chronic inflammatory nature of psoriasis has been suggested to be a contributing and potentially independent risk factor for the development of cardiovascular comorbidities. Understanding the interrelationship between these conditions is important for the management of psoriasis and the associated comorbidities. This review will focus on the range of comorbidities associated with psoriasis, with emphasis on cardiometabolic conditions and the aim of encouraging primary care physicians to screen psoriatic patients for cardiometabolic disorders and risk factors. (C) 2009 Elsevier Inc. All rights reserved. The American Journal of Medicine (2009) 122, 1150.e1-1150.e9
引用
收藏
页码:1150.e1 / 1150.e9
页数:9
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