Origin of spectral tuning in rhodopsin - It is not the binding pocket

被引：80

作者：

Sekharan, Sivakumar ^{[1
]}

Sugihara, Minoru ^{[1
]}

Buss, Volker ^{[1
]}

机构：

[1] Univ Duisburg Essen, Dept Chem & Phys, D-47048 Duisburg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 1-2期

关键词：

ab initio calculations; absorbance; rhodopsin; spectral tuning; visual pigments;

D O I：

10.1002/anie.200603306

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The counterion, not the binding pocket, shifts the absorption of the protonated Schiff base of 11-cis-retinal into the visible region. This conclusion was drawn from high-level CASPT2 calculations on the visual pigment rhodopsin (the optimized structure of the binding pocket is shown). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：269 / 271

页数：3

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