Origin of spectral tuning in rhodopsin - It is not the binding pocket

被引:80
作者
Sekharan, Sivakumar [1 ]
Sugihara, Minoru [1 ]
Buss, Volker [1 ]
机构
[1] Univ Duisburg Essen, Dept Chem & Phys, D-47048 Duisburg, Germany
关键词
ab initio calculations; absorbance; rhodopsin; spectral tuning; visual pigments;
D O I
10.1002/anie.200603306
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) The counterion, not the binding pocket, shifts the absorption of the protonated Schiff base of 11-cis-retinal into the visible region. This conclusion was drawn from high-level CASPT2 calculations on the visual pigment rhodopsin (the optimized structure of the binding pocket is shown). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:269 / 271
页数:3
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