We analyze the chemical composition and abundances of comets based on in situ measurements of Comet 1P/Halley and remote sensing observations of several recent bright comets including Hale-Bopp (C/1995 O1) and Hyakutake (C/1996 B2), in light of the elemental abundances of the solar system. Nitrogen is underabundant in comets relative to the solar system because nitrogen tends to be in N-2, which is chemically relatively inert. While many details remain uncertain, some gross features are emerging. The abundance of water : silicates: carbonaceous molecules (CO, CO2, and hydrocarbons) by mass is approximately 1:1:1. Furthermore, the mass abundance of ice : dust ( silicates and hydrocarbon polycondensates) is about 1:1. We compare a list of identified comet molecules with molecules detected in the interstellar medium, although a comparison with their relative abundances, particularly in the ice phase, would be more meaningful. However, ice-phase abundances are not yet available. One can expect a variation of the abundances of carbon-bearing molecules in comets to be associated with their place of origin in the solar nebula. However, we also note that comets are heterogeneous. Thus, observed differences may be related to the place of origin, heterogeneity of the nucleus, or acquired through evolution. The molecular and elemental compositions of the coma are most likely not the same as those in the nucleus. This is particularly true for volatile ices and their gases and for the dust-to-ice and dust-to-gas ratios. Analyses must carefully consider the three sources of gas: Water from the surface of the nucleus, gases more volatile than water from the interior of the nucleus, and gases from the sublimation of the dust distributed in the coma. Topography on the surface of the nucleus may cause important evolutionary differences in the dust-to-gas mass ratio. Relatively inactive areas on the surface of the nucleus are probably associated with convex topography. Gas sublimated from convex areas ( hills and mountains) diverges more strongly relative to gas sublimated from concave areas, which can entrain dust more efficiently. Thus, the entrainment of dust from convex areas is poor and dust may fall back to the surface of the nucleus creating a dust mantle, which further inhibits outgassing.
