Cell Lines as Biological Models: Practical Steps for More Reliable Research

被引:18
作者
Capes-Davis, Amanda [1 ]
Bairoch, Amos [2 ,3 ]
Barrett, Tanya [4 ]
Burnett, Edward C. [5 ]
Dirks, Wilhelm G. [6 ]
Hall, Erin M. [7 ]
Healy, Lyn [8 ]
Kniss, Douglas A. [9 ]
Korch, Christopher [10 ]
Liu, Yuqin [11 ,12 ]
Neve, Richard M. [13 ]
Nims, Raymond W. [14 ]
Parodi, Barbara [15 ]
Schweppe, Rebecca E. [16 ]
Storts, Douglas R. [17 ]
Tian, Fang [18 ]
机构
[1] Univ Sydney, CellBank Australia, Childrens Med Res Inst, Westmead, NSW 2145, Australia
[2] Univ Geneva, SIB, CH-1205 Geneva, Switzerland
[3] Univ Geneva, Fac Med, CH-1205 Geneva, Switzerland
[4] NCBI, NLM, NIH, Bethesda, MD 20894 USA
[5] Culture Collect Publ Hlth England, Porton Down SP4 0JG, England
[6] Leibniz Inst DSMZ, D-38124 Braunschweig, Germany
[7] Genet Cell Line Testing, Burlington, NC 27215 USA
[8] Francis Crick Inst, London NW1 1AT, England
[9] Ohio State Univ, Columbus, OH 43210 USA
[10] Univ Colorado, Div Med Oncol, Anschutz Med Campus, Aurora, CO 80045 USA
[11] Chinese Acad Med Sci, Inst Basic Med Sci, Beijing, Peoples R China
[12] Peking Union Med Coll, Sch Basic Med, Beijing, Peoples R China
[13] Gilead Sci Inc, Foster City, CA 94404 USA
[14] RMC Pharmaceut Solut Inc, Longmont, CO 80501 USA
[15] IRCCS Osped Policlin San Martino, I-16132 Genoa, Italy
[16] Univ Colorado, Div Med Endocrinol Metab & Diabet, Anschutz Med Campus, Aurora, CO 80045 USA
[17] Promega Corp, Madison, WI 53711 USA
[18] ATCC, Manassas, VA 20110 USA
关键词
D O I
10.1021/acs.chemrestox.9b00215
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Research in toxicology relies on in vitro models such as cell lines. These living models are prone to change and may be described in publications with insufficient information or quality control testing. This article sets out recommendations to improve the reliability of cell-based research.
引用
收藏
页码:1733 / 1736
页数:4
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