The Emergence of Kidney Stone Disease During Childhood-Impact on Adults

被引:20
作者
Bonzo, Jeremy R. [1 ]
Tasian, Gregory E. [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Univ Penn, Dept Surg, Div Urol, Perelman Sch Med, Philadelphia, PA 19104 USA
[2] Childrens Hosp Philadelphia, Dept Surg, Div Pediat Urol, Philadelphia, PA 19104 USA
[3] Childrens Hosp Philadelphia, Ctr Pediat Clin Effectiveness, Philadelphia, PA 19104 USA
[4] Univ Penn, Ctr Clin Epidemiol & Biostat, Perelman Sch Med, Philadelphia, PA 19104 USA
[5] Univ Penn, Dept Biostat & Epidemiol, Perelman Sch Med, Philadelphia, PA 19104 USA
[6] Childrens Hosp Philadelphia, Div Urol, Wood Ctr, 34th St & Civ Ctr Blvd,3rd Floor, Philadelphia, PA 19104 USA
关键词
Nephrolithiasis; Children; Extrarenal manifestations; Stone prevention; Transition of care; BONE-MINERAL DENSITY; REGIONAL-VARIATION; PEDIATRIC-PATIENTS; UNITED-STATES; NEPHROLITHIASIS; CHILDREN; POPULATION; RISK; UROLITHIASIS; PREVALENCE;
D O I
10.1007/s11934-017-0691-x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose of Review The goal of this chapter is to review the recent epidemiologic trends of kidney stone disease and discuss the impact of the increasing incidence of nephrolithiasis among children on adults with respect to extra-renal manifestations, surgical management, and secondary prevention. Recent Findings Among pediatric patients, kidney stone disease has been increasing at a rate of approximately 5-10% annually. Kidney stone disease has been associated with increased risks of coronary heart disease, chronic kidney disease, hypertension, and decreased bone mineral density, which is concerning for patients diagnosed at a young age. Improvements in endo-urology have allowed for less invasive surgical treatment of stones in the pediatric population. However, current guidelines often lack recommendations for evaluation, medical, and surgical management of children with kidney stone disease. Summary Nephrolithiasis is a disorder of mineral metabolism, which is beginning during childhood with increasing frequency. Kidney stone disease often exists over the lifetime and is associated with serious conditions that are important for pediatric and adult urologists to recognize and consider in their evaluation and treatment of patients.
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