Chemically Functionalized Carbon Nanotubes: Emerging Vectors for Cell Therapy

被引：10
作者：
Ciofani, Gianni [1 ]
Raffa, Vittoria [1 ]
机构：
[1] Scuola Super Sant Anna, I-56127 Pisa, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2009年 / 9卷 / 11期
关键词：
Carbon nanotubes; nanovectors; biomedical applications; functionalization; drug delivery; gene delivery; cellular up-take; biodistribution; IN-VIVO; DRUG-DELIVERY; BIODISTRIBUTION; DNA; NANOMEDICINES; TRANSPORTERS; INTERNALIZATION; IMMOBILIZATION; TRANSLOCATION; FLUORESCENCE;
D O I：
10.2174/138955709789878132
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Carbon nanotubes are widely used for biomedical applications as intracellular transporters of biomolecules, due to their high propensity to cross cell membranes. In this review we summarize the recent advancement in the functionalization of carbon nanotubes, focusing particular attention on the chemistry involved in the preparation of nanovectors for drug delivery systems, and on the physical and chemical properties that affect cellular up-take and biodistribution phenomena.
引用
收藏
页码：1251 / 1261
页数：11
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