Molecular recognition and catalysis: Incorporation of an ''oxyanion hole'' into a synthetic receptor

被引：0

作者：

Fan, EK ^{[1
]}

Vicent, C ^{[1
]}

Hamilton, AD ^{[1
]}

机构：

[1] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA

来源：

NEW JOURNAL OF CHEMISTRY | 1997年 / 21卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Acceleration of the 1,4-addition of a thiol to a maleimide can be achieved by binding the electrophile into a synthetic receptor containing hydrogen bonding sites that can interact with the carbonyl group and so stabilize the developing oxyanion in the transition state.

引用

页码：81 / 85

页数：5

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