Green synthesis of silver nanoparticles using Solanum indicum L. and their antibacterial, splenocyte cytotoxic potentials

被引:59
|
作者
Sengottaiyan, A. [1 ]
Mythili, R. [1 ,2 ]
Selvankumar, T. [1 ]
Aravinthan, A. [2 ]
Kamala-Kannan, S. [3 ]
Manoharan, K. [4 ]
Thiyagarajan, P. [1 ]
Govarthanan, Muthusamy [1 ,3 ]
Kim, Jong-Hoon [2 ]
机构
[1] Mahendra Arts & Sci Coll Autonomous, PG & Res Dept Biotechnol, Namakkal 637501, Tamil Nadu, India
[2] Chonbuk Natl Univ, Biosafety Res Inst, Coll Vet Med, Iksan 570752, South Korea
[3] Chonbuk Natl Univ, Coll Environm & Bioresource Sci, Div Biotechnol, Adv Inst Environm & Biosci, Iksan 570752, South Korea
[4] Raja Duraisingam Govt Arts Coll, Dept Bot, Sivagangai 630560, Tamil Nadu, India
基金
新加坡国家研究基金会;
关键词
Silver; Nanoparticles; Green synthesis; S. indicum L; BIOSYNTHESIS; EXTRACT; GOLD;
D O I
10.1007/s11164-015-2199-7
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Green synthesis of silver nanoparticles was carried out using Solanum indicum L. plant extract as a reducing agent. The morphology of the AgNPs was determined by transmission electron microscopy. Scanning electron microscopy and energy-dispersive spectroscopy (EDX) were used to characterize the nanoparticles obtained from S. indicum L. The EDX analysis of the nanoparticles dispersion, using a range of 2-4 keV, confirmed the presence of elemental silver, without any contamination. The green synthesized AgNPs were evaluated against the pathogens such as Staphylococcus sp., (Accession No. KC688883) and Klebsiella sp., (Accession No. KC899845). The AgNPs (1-4 mM) extensively inhibit the growth of the pathogens. Cytotoxic potential of the synthesized AgNPs was analyzed against rat splenocytes. The percentage of viable cells was diminished according to the increasing concentration of AgNPs.
引用
收藏
页码:3095 / 3103
页数:9
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