Treatment non-adherence in teenage and young adult cancer patients: a preliminary study of patient perceptions

被引:16
作者
Kondryn, Helena J. [1 ]
Edmondson, Claire L. [1 ]
Hill, Jonathan W. [2 ]
Eden, Tim O. B. [1 ]
机构
[1] Univ Manchester, Acad Unit Paediat & Adolescent Oncol, Sch Canc Studies & Imaging, Manchester M13 9PL, Lancs, England
[2] Univ Manchester, Sch Med, Manchester M13 9PL, Lancs, England
关键词
cancer; oncology; non-adherence; adherence; adolescent; young adult; ADHERENCE; ADOLESCENTS; LEUKEMIA; NONCOMPLIANCE; CHILDREN; THERAPY; FOCUS;
D O I
10.1002/pon.1541
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives: Non-adherence (NA) by adolescents receiving cancer treatment is believed to be a major problem. However, adequate measures of NA have not been developed. The purpose of this study was to (1) assess the internal reliability of a new scale reflecting low-risk NA behaviours, (2) examine whether the scores on this scale were associated with high-risk NA behaviours and (3) assess the relationship between NA behaviours and patient attitudes towards stopping treatment. Methods: Thirty-three patients (16-24 years) with solid tumours reported on their previous adherence with treatment. Low-risk NA behaviours were assessed on a 0-40 scale derived from the sum of 10 items. High-risk NA behaviours and attitudes towards stopping treatment were assessed by questions with yes/no response options. Results: Internal reliability of the low-risk NA scale was alpha = 0.73. Patients not seeking help for pyrexia had higher total low-risk NA scores than those who sought help (mean 7.4, SD 5.3 vs mean 3.5, SD 3.6, t = 2.1, p = 0.03). There was also a trend for individuals who ignored pyrexia to be more likely to have contemplated stopping treatment than those who sought medical assistance (Fisher's Exact = 0.09). Conclusions: A scale reflecting low-risk NA behaviour had good internal reliability and was associated with not seeking help when pyrexic. Ignoring a temperature was also associated with contemplating stopping treatment. We are now conducting a prospective study using the measure to assess validity against a range of information regarding NA. Copyright (C) 2009 John Wiley & Sons, Ltd.
引用
收藏
页码:1327 / 1332
页数:6
相关论文
共 21 条
[1]  
[Anonymous], 2005, ADHERENCE LONG TERM
[2]   Classification and incidence of cancers in adolescents and young adults in England 1979-1997 [J].
Birch, JM ;
Alston, RD ;
Kelsey, AM ;
Quinn, MJ ;
Babb, P ;
McNally, RJQ .
BRITISH JOURNAL OF CANCER, 2002, 87 (11) :1267-1274
[3]  
CROMER BA, 1989, J DEV BEHAV PEDIATR, V10, P207
[4]   VARIABLE MERCAPTOPURINE METABOLISM IN CHILDREN WITH LEUKEMIA - A PROBLEM OF NONCOMPLIANCE [J].
DAVIES, HA ;
LENNARD, L ;
LILLEYMAN, JS .
BRITISH MEDICAL JOURNAL, 1993, 306 (6887) :1239-1240
[5]   Clinical and laboratory evaluation of compliance in acute lymphoblastic leukaemia [J].
de Oliveira, BM ;
Viana, MB ;
Zani, CL ;
Romanha, AJ .
ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (08) :785-788
[6]   CAREGIVERS PERCEPTIONS OF MEDICAL COMPLIANCE IN ADOLESCENTS WITH CANCER [J].
DOLGIN, MJ ;
KATZ, ER ;
DOCTORS, SR ;
SIEGEL, SE .
JOURNAL OF ADOLESCENT HEALTH, 1986, 7 (01) :22-27
[7]   FOCUS ON PSYCHOMETRICS - ASPECTS OF ITEM ANALYSIS [J].
FERKETICH, S .
RESEARCH IN NURSING & HEALTH, 1991, 14 (02) :165-168
[8]  
GILBERT JR, 1980, CAN MED ASSOC J, V123, P119
[9]  
Hanna K M, 1993, Issues Compr Pediatr Nurs, V16, P219, DOI 10.3109/01460869309078279
[10]   COOPERATION WITH TREATMENT IN ADOLESCENT CANCER-PATIENTS [J].
JAMISON, RN ;
LEWIS, S ;
BURISH, TG .
JOURNAL OF ADOLESCENT HEALTH, 1986, 7 (03) :162-167