Involvement of the claustrum in the convulsive evolution of temporal limbic seizure in feline amygdaloid kindling

被引：20

作者：

Wada, JA ^{[1
]}

Kudo, T ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,DIV NEUROL,VANCOUVER,BC V6T 2A1,CANADA

来源：

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1997年 / 103卷 / 02期

基金：

英国医学研究理事会;

关键词：

claustral; amygdaloid kindling; convulsive evolution; kindled convulsion;

D O I：

10.1016/S0013-4694(97)96160-5

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The effects of unilateral lesioning of the claustrum (CL) either prior to or following completion of amygdaloid (AM) kindling was examined in cats. CL lesioning ipsilateral to the kindling or the kindled AM caused the emergence of a mirror image pattern of expected or established AM onset convulsive seizure originating in the contralateral hemisphere. This finding suggests that: (1) the CL is involved in the convulsive evolution of AM onset non-convulsive limbic seizure; (2) an alternative transhemispheric route is available for the convulsive evolution of AM onset limbic seizure when the ipsilateral CL is disrupted; and (3) the CL is not critical for secondary convulsive generalization. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：249 / 256

页数：8