Synthesis, Structure, and Biological Activity of Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) with N-(Methoxyphenyl)-2-[(5-nitrofuryl)methylene]hydrazine Carbothioamides

被引：2
|
作者：
Gulea, A. P. [1 ]
Mitkevich, N. L. [1 ]
Chumakov, Yu. M. [2 ,3 ]
Petrenko, P. A. [2 ]
Balan, G. G. [4 ]
Burduniuc, O. S. [4 ,5 ]
Tsapkov, V. I. [1 ]
机构：
[1] State Univ Moldova, Ul Mateevicha 60, Kishinev, Moldova
[2] Inst Appl Phys, Kishinev, Moldova
[3] Gebze Inst Technol, Kocaeli, Turkey
[4] State Univ Med & Pharm Nicolae Testemitanu, Kishinev, Moldova
[5] Natl Agcy Publ Hlth, Kishinev, Moldova
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2019年 / 89卷 / 07期
关键词：
cobalt(II) complexes; nickel(II) complexes; copper(II) complexes; hydrazine carbothioamides; crystal structure; antimicrobial activity; antifungal activity; IN-VITRO ANTILEUKEMIA; METAL-COMPLEXES; ANTIBACTERIAL; ANTIFUNGAL; THIOSEMICARBAZONES;
D O I：
10.1134/S1070363219070119
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
4-(2-Methoxyphenyl)-, 4-(3-methoxyphenyl)-, and 4-(4-memoxyphenyl)-2-[(5-mttofuryl)methylene]-hydrazine carboxamide (HL1-3) react with hydrates of cobalt (nickel, copper) chloride (nitrate, acetate) with the formation of the M(HL1-3)(2)X-2 (M = Co2+, Ni2+, Cu2+; X = Cl-, NO3-) and M(L1-3)(2) (M = Ni2+, Cu2+) coordination compounds. Structure of the obtained compounds has been studied by means of X-ray diffraction analysis. Their antimicrobial and antifungal activity towards a series of Staphylococcus aureus, Escherichia coli, and yeast-like fungi standard strains has been investigated.
引用
收藏
页码：1415 / 1423
页数：9
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