The Helicobacter pylori Mfd protein is important for antibiotic resistance and DNA repair

被引：17

作者：

Lee, Gin Hyug ^{[1
]}

Jeong, Jin-Yong ^{[2
]}

Chung, Jun-Won ^{[1
]}

Nam, Won-Hee ^{[2
]}

Lee, Sun-Mi ^{[2
]}

Pak, Jhang-Ho ^{[2
]}

Choi, Kee Don ^{[1
]}

Song, Ho June ^{[1
]}

Jung, Hwoon-Yong ^{[1
]}

Kim, Jin-Ho ^{[1
]}

机构：

[1] Univ Ulsan, Asan Med Ctr, Div Gastroenterol, Dept Internal Med,Coll Med, Seoul 138736, South Korea

[2] Univ Ulsan, Asan Med Ctr, Asan Inst Life Sci, Coll Med, Seoul 138736, South Korea

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2009年 / 65卷 / 04期

关键词：

Helicobacter pylori; Antibiotic resistance; DNA repair; EXCISION; MUTANT;

D O I：

10.1016/j.diagmicrobio.2009.08.007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A Helicobacter pylori mutant defective in a putative mfd gene was constructed and characterized. The mfd gene is required for DNA repair and is involved in DNA recombination processes. The mfd mutant strain displayed a greatly increased susceptibility to antibiotics, indicating that this gene plays a significant role in the antibiotic resistance of H. pylori strain J99. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：454 / 456

页数：3

共 50 条

[21] Helicobacter pylori Antibiotic Resistance: Molecular Basis and Diagnostic Methods
Medakina, Irina
Tsapkova, Larisa
Polyakova, Vera
Nikolaev, Sergey
Yanova, Tatyana
Dekhnich, Natalia
Khatkov, Igor
Bordin, Dmitry
Bodunova, Natalia
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (11)
[22] Antibiotic resistance of Helicobacter pylori to 16 antibiotics in clinical patients
Shao, Yongfu
Lu, Rongdan
Yang, Yunben
Xu, Qiancheng
Wang, Bojun
Ye, Guoliang
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2018, 32 (04)
[23] Virulence Factors and Antibiotic Resistance in Children With Helicobacter pylori Gastritis
Karabiber, Hamza
Selimoglu, Mukadder A.
Otlu, Baris
Yildirim, Ozge
Ozer, Ali
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2014, 58 (05) : 608 - 612
[24] Implications of antibiotic resistance in the management of Helicobacter pylori infection:: Canadian Helicobacter Study Group
Hunt, RH
SMaill, FM
Fallone, CA
Sherman, PM
van Zanten, SJV
Thomson, ABR
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2000, 14 (10) : 862 - 868
[25] Antibiotic susceptibilities of Helicobacter pylori
Bindayna, KM
SAUDI MEDICAL JOURNAL, 2001, 22 (01) : 53 - 57
[26] Antibiotic resistance and cagA gene correlation:A looming crisis of Helicobacter pylori
Adnan Khan
Amber Farooqui
Hamid Manzoor
Syed Shakeel Akhtar
Muhammad Saeed Quraishy
Shahana Urooj Kazmi
World Journal of Gastroenterology, 2012, 18 (18) : 2245 - 2252
[27] High Prevalence of Primary Antibiotic Resistance in Helicobacter pylori Isolates in Italy
Saracino, Ilaria M.
Zullo, Angelo
Holton, John
Castelli, Valentina
Fiorini, Giulia
Zaccaro, Cristina
Ridola, Lorenzo
Ricci, Chiara
Gattas, Luigi
Vaira, Dino
JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES, 2012, 21 (04) : 363 - 365
[28] Increased Antibiotic Resistance in Children with Helicobacter pylori Infection: A Retrospective Study
Helmbold, Luca
Ghebremedhin, Beniam
Bellm, Aliyah
Hopkins, Marc A.
Wirth, Stefan
Aydin, Malik
PATHOGENS, 2022, 11 (02):
[29] The influence of efflux pump on the antibiotic resistance of Helicobacter pylori to clarithromycin and moxifloxacin
Lee, Sun Min
Kim, Nayoung
Kwon, Yong Hwan
Nam, Ryoung Hee
Suh, Ji Hyung
Ham, Min Hee
Kim, Sujin
Lee, Jong-Chan
Park, Jong Youn
Lee, Dong Ho
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2015, 30 : 3 - 4
[30] Clinical Implications of Helicobacter pylori Antibiotic Resistance in Italy: A Review of the Literature
Nista, Enrico Celestino
Pellegrino, Antonio
Giuli, Lucia
Candelli, Marcello
Schepis, Tommaso
De Lucia, Sara Sofia
Ojetti, Veronica
Franceschi, Francesco
Gasbarrini, Antonio
ANTIBIOTICS-BASEL, 2022, 11 (10):

← 1 2 3 4 5 →