Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting

被引：2

作者：

Krueger, James G. ^{[1
]}

Kirkham, Bruce

Ritchlin, Christopher T.

机构：

[1] Rockefeller Univ, Clin Invest, 1230 York Ave, New York, NY 10021 USA

来源：

JOURNAL OF RHEUMATOLOGY | 2017年 / 44卷 / 05期

关键词：

PSORIATIC ARTHRITIS; PSORIASIS; GRAPPA; INNATE LYMPHOID-CELLS; PSORIATIC-ARTHRITIS; DISEASE-ACTIVITY; PATHOGENESIS; SKIN; AUTOIMMUNE; INFLAMMATION; JOINTS;

D O I：

10.3899/jrheum.170143

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rapid advances in effective treatments for psoriasis and psoriatic arthritis (PsA) have emerged from improved understanding of cell subsets and critical mediators that promote tissue inflammation and destruction. More specifically, increased knowledge of innate immunity and the important involvement of cytokines in the interleukin (IL)-23-IL-17 axis as key mediators of psoriatic plaque and joint inflammation in both psoriasis and PsA have led to new theories of immunopathogenesis. Herein we summarize recent discussions on IL-17-related pathways and their relationship to psoriasis and PsA.

引用

页码：679 / 683

页数：5

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