Three-component condensation of diethyl isophthaloyldiacetate, aromatic aldehyde, and urea as a new method for the synthesis of 1,3-bis(2-oxo-1,2,3,4-tetrahydropyrimidin-6-yl)benzenes

被引：3

作者：

Mamedov, V. A. ^{[1
]}

Vdovina, S. V. ^{[1
]}

Vorkunova, E. I. ^{[1
]}

Mustakimova, L. V. ^{[1
]}

Saifina, A. F. ^{[1
]}

Gubaidullin, A. T. ^{[1
]}

Rizvanov, I. Kh. ^{[1
]}

Levin, Ya. A. ^{[1
]}

Litvinov, I. A. ^{[1
]}

机构：

[1] Russian Acad Sci, Kazan Sci Ctr, AE Arbuzov Organ & Phys Chem Inst, Kazan 420088, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2008年 / 57卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

diethyl isophthaloyldiacetate; the Biginelli reaction; 2-oxo-1,2,3,4-tetrahydropyrimidines; trimethylsilyl chloride; NMR spectra; X-ray analysis;

D O I：

10.1007/s11172-008-0161-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Condensation of diethyl isophthaloyldiacetate, aromatic aldehyde, and urea in the presence of Me3SiCl proceeds efficiently and faster than in the absence of the latter to form 1,3-bis(2-oxo-1,2,3,4-tetrahydropyrimidin-6-yl)benzene derivatives capable to give inclusion complexes with DMF.

引用

页码：1257 / 1263

页数：7

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