Determination of fraction unbound docetaxel using microequilibrium dialysis

被引:16
作者
Acharya, MR
Baker, SD
Verweij, J
Figg, WD [1 ]
Sparreboom, A
机构
[1] NCI, Clin Pharmacol Res Ctr, Bethesda, MD 20892 USA
[2] Johns Hopkins Univ, Sidney Kimmel Co mprehens Canc Ctr, Div Expt Therapeut, Baltimore, MD USA
[3] Erasmus Univ MC, Dr Daniel Den Hoed Canc Ctr, Dept Med Oncol, Rotterdam, Netherlands
关键词
D O I
10.1016/j.ab.2004.03.045
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:192 / 194
页数:3
相关论文
共 50 条
[21]   Determination of the unbound fraction of R- and S-methadone in human brain [J].
Holm, Karen M. D. ;
Linnet, Kristian .
INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2016, 130 (06) :1519-1526
[22]   Determination of the unbound fraction of R- and S-methadone in human brain [J].
Xiulu Ruan ;
Ken F. Mancuso ;
Alan David Kaye .
International Journal of Legal Medicine, 2017, 131 :391-392
[23]   Direct determination of the ratio of unbound fraction in plasma to unbound fraction in microsomal system (fup/fumic) for refined prediction of phase I mediated metabolic hepatic clearance [J].
Deshmukh, Sujal V. ;
Harsch, Andreas .
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2011, 63 (01) :35-39
[24]   Accurate prediction of the unbound drug fraction in assay medium from the unbound drug fraction in plasma [J].
Niwa-Sakai, Michiko ;
Jinno, Norimasa ;
Takashima, Tadayuki ;
Ohashi, Shigeki ;
Tagashira, Mizuka ;
Tsurui, Kazuyuki .
DRUG METABOLISM REVIEWS, 2016, 48 :58-58
[25]   Comment: unbound drug concentration versus unbound drug fraction [J].
Ensom, MHH .
ANNALS OF PHARMACOTHERAPY, 2002, 36 (04) :731-732
[26]   Determination of unbound docetaxel and paclitaxel in plasma by ultrafiltration and liquid chromatography-tandem mass spectrometry [J].
Mortier, KA ;
Lambert, WE .
JOURNAL OF CHROMATOGRAPHY A, 2006, 1108 (02) :195-201
[27]   Relationship of systemic exposure to unbound docetaxel and neutropenia [J].
Baker, SD ;
Li, J ;
ten Tije, AJ ;
Figg, WD ;
Graveland, W ;
Verweij, J ;
Sparreboom, A .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 77 (01) :43-53
[28]   Improving Confidence in the Determination of Free Fraction for Highly Bound Drugs Using Bidirectional Equilibrium Dialysis [J].
Chen, Yi-Chen ;
Kenny, Jane R. ;
Wright, Matthew ;
Hop, Cornelis E. C. A. ;
Yan, Zhengyin .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 108 (03) :1296-1302
[29]   MICROSCALE ULTRACENTRIFUGATION AS AN ALTERNATIVE TO ULTRAFILTRATION FOR THE DETERMINATION OF THE UNBOUND FRACTION OF PHENYTOIN IN HUMAN-SERUM [J].
JACK, L ;
CUNNINGHAM, C ;
WATSON, ID ;
STEWART, MJ .
ANNALS OF CLINICAL BIOCHEMISTRY, 1986, 23 :603-607
[30]   Comment: unbound drug concentration versus unbound drug fraction - Reply [J].
Boothby, LA ;
Doering, PL .
ANNALS OF PHARMACOTHERAPY, 2002, 36 (04) :732-732