Feed conversion ratio, residual feed intake and cholecystokinin type A receptor gene polymorphisms are associated with feed intake and average daily gain in a Chinese local chicken population

被引：61

作者：

Yi, Zhenhua ^{[1
,2
,3
]}

Li, Xing ^{[1
,2
,3
]}

Luo, Wen ^{[1
,2
,3
]}

Xu, Zhenqiang ^{[4
]}

Ji, Congliang ^{[4
]}

Zhang, Yan ^{[4
]}

Nie, Qinghua ^{[1
,2
,3
]}

Zhang, Dexiang ^{[1
,2
,3
,4
]}

Zhang, Xiquan ^{[1
,2
,3
]}

机构：

[1] South China Agr Univ, Coll Anim Sci, Dept Anim Genet Breeding & Reprod, Guangzhou 510642, Guangdong, Peoples R China

[2] Minist Agr, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangzhou 510642, Guangdong, Peoples R China

[3] Minist Agr, Key Lab Chicken Genet Breeding & Reprod, Guangzhou 510642, Guangdong, Peoples R China

[4] Wens Nanfang Poultry Breeding Co Ltd, Yunfu 527400, Guangdong, Peoples R China

来源：

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY | 2018年 / 9卷

关键词：

CCKAR; Chicken; FCR; RFI; SNP; MEAT-TYPE CHICKENS; FOOD-INTAKE; BODY-WEIGHT; TRANSCRIPTOMIC ANALYSIS; STATISTICAL PROPERTIES; EFFICIENCY TRAITS; GROWTH; PARAMETERS; SELECTION; CATTLE;

D O I：

10.1186/s40104-018-0261-1

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Background: The feed conversion ratio (FCR) and residual feed intake (RFI) are common indexes in measuring feed efficiency for livestock RFI is a feed intake adjusted for requirements for maintenance and production so these two traits are related. Similarly, FCR is related to feed intake and weight gain because it is their ratio. Cholecystokinin type A receptor (CCKAR) plays an important role in animal digestive process. We examined the interplay of these three parameters in a local Chinese chicken population. Results: The feed intake (FI) and body weights (BW) of 1,841 individuals were monitored on a daily basis from 56 to 105 d of age. There was a strong correlation between RFI and average daily feed intake (ADFI) and a negative correlation between the FCR and daily gain (r(g) = -0.710). Furthermore, we identified 51 single nucleotide polymorphisms (SNPs) in the CCKAR and 4 of these resulted in amino acid mutations. The C334A mutation was specifically associated with Fl and the expected feed intake (EFI) (P < 0.01) and significantly associated with the average daily gain (ADG) (P < 0.05). G1290A was significantly associated with Fl and EFI (P < 0.05). Conclusion: FCR is apply to weight selecting, and RFI is more appropriate if the breeding focus is feed intake. And C334A and G1290A of the CCKAR gene can be deemed as candidate markers for feed intake and weight gain.

引用

页数：9

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