Mass spectrometry of natural products: current, emerging and future technologies

被引:151
作者
Bouslimani, Amina [2 ]
Sanchez, Laura M. [2 ]
Garg, Neha [2 ]
Dorrestein, Pieter C. [1 ,2 ]
机构
[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA
基金
美国国家卫生研究院;
关键词
DESORPTION ELECTROSPRAY-IONIZATION; FUNGAL SECONDARY METABOLITES; HIGH-RESOLUTION; STREPTOMYCES-COELICOLOR; AMBIENT CONDITIONS; ION-TRAP; NONRIBOSOMAL PEPTIDES; MOLECULAR NETWORKING; FRAGMENTATION TREES; BACILLUS-SUBTILIS;
D O I
10.1039/c4np00044g
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Although mass spectrometry is a century old technology, we are entering into an exciting time for the analysis of molecular information directly from complex biological systems. In this Highlight, we feature emerging mass spectrometric methods and tools used by the natural product community and give a perspective of future directions where the mass spectrometry field is migrating towards over the next decade.
引用
收藏
页码:718 / 729
页数:12
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