Mass spectrometry of natural products: current, emerging and future technologies

被引：151
作者：
Bouslimani, Amina [2 ]
Sanchez, Laura M. [2 ]
Garg, Neha [2 ]
Dorrestein, Pieter C. [1 ,2 ]
机构：
[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA
来源：
NATURAL PRODUCT REPORTS | 2014年 / 31卷 / 06期
基金：
美国国家卫生研究院;
关键词：
DESORPTION ELECTROSPRAY-IONIZATION; FUNGAL SECONDARY METABOLITES; HIGH-RESOLUTION; STREPTOMYCES-COELICOLOR; AMBIENT CONDITIONS; ION-TRAP; NONRIBOSOMAL PEPTIDES; MOLECULAR NETWORKING; FRAGMENTATION TREES; BACILLUS-SUBTILIS;
D O I：
10.1039/c4np00044g
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Although mass spectrometry is a century old technology, we are entering into an exciting time for the analysis of molecular information directly from complex biological systems. In this Highlight, we feature emerging mass spectrometric methods and tools used by the natural product community and give a perspective of future directions where the mass spectrometry field is migrating towards over the next decade.
引用
收藏
页码：718 / 729
页数：12
相关论文
共 111 条
  • [1] Segmentation of Confocal Raman Microspectroscopic Imaging Data Using Edge-Preserving Denoising and Clustering
    Alexandrov, Theodore
    Lasch, Peter
    [J]. ANALYTICAL CHEMISTRY, 2013, 85 (12) : 5676 - 5683
  • [2] Efficient spatial segmentation of large imaging mass spectrometry datasets with spatially aware clustering
    Alexandrov, Theodore
    Kobarg, Jan Hendrik
    [J]. BIOINFORMATICS, 2011, 27 (13) : I230 - I238
  • [3] Examination of the distribution of nicosulfuron in sunflower plants by matrix-assisted laser desorption/ionisation mass spectrometry imaging
    Anderson, David M. G.
    Carolan, Vikki A.
    Crosland, Susan
    Sharples, Kate R.
    Clench, Malcolm R.
    [J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2009, 23 (09) : 1321 - 1327
  • [4] [Anonymous], ANTIBASE DATA BASE R
  • [5] [Anonymous], 2013, Dictionary of Natural Products 24.2
  • [6] Bandeira N., 2008, BIOINFORMATICS, V24, pi416, DOI [10.1093/bioinformatics/btn184, DOI 10.1093/BIOINFORMATICS/BTN184]
  • [7] A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus
    Barke, Joerg
    Seipke, Ryan F.
    Grueschow, Sabine
    Heavens, Darren
    Drou, Nizar
    Bibb, Mervyn J.
    Goss, Rebecca J. M.
    Yu, Douglas W.
    Hutchings, Matthew I.
    [J]. BMC BIOLOGY, 2010, 8
  • [8] Fractionated marine invertebrate extract libraries for drug discovery
    Bugni, Tim S.
    Harper, Mary Kay
    McCulloch, Malcolm W. B.
    Reppart, Jason
    Ireland, Chris M.
    [J]. MOLECULES, 2008, 13 (06): : 1372 - 1383
  • [9] Bugni TS, 2010, RSC BIOMOL SCI, P272
  • [10] Molecular imaging of biological samples: Localization of peptides and proteins using MALDI-TOF MS
    Caprioli, RM
    Farmer, TB
    Gile, J
    [J]. ANALYTICAL CHEMISTRY, 1997, 69 (23) : 4751 - 4760
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