COVID-19 in a patient with a flare of systemic lupus erythematosus: A rare case-report

被引:16
作者
Alharthy, Abdulrahman [1 ]
Faqihi, Fahad [1 ]
Nasim, Nasir [1 ]
Noor, Alfateh [1 ]
Akhtar, Saima [1 ]
Balshi, Ahmed [1 ]
Balhamar, Abdullah [1 ]
Alqahtani, Saleh A. [2 ]
Memish, Ziad A. [3 ]
Karakitsos, Dimitrios [1 ,4 ]
机构
[1] King Saud Med City, Crit Care Dept, POB 331905, Riyadh 11373, Saudi Arabia
[2] Johns Hopkins Univ Hosp, Dept Med, Baltimore, MD 21205 USA
[3] King Saud Med City, Res & Innovat Ctr, Riyadh, Saudi Arabia
[4] South Carolina Univ, Sch Med, Dept Internal Med, Columbia, SC USA
关键词
COVID-19; Systemic lupus erythematosus; Acute respiratory failure; End-stage kidney disease; Steroid therapy; Hydroxychloroquine;
D O I
10.1016/j.rmcr.2020.101252
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
This is a rare case-report of a young female with systemic lupus erythematosus and end-stage kidney disease (on maintenance hemodialysis) who was admitted to our intensive care unit due to life-threatening COVID-19. The patient was diagnosed with a flare of lupus; while being on maintenance hydroxychloroquine therapy. However, after the administration of steroids she made an uneventful recovery and was discharged home. In this report, the diagnostic dilemmas and the therapeutic challenges due to the overlapping clinical, imaging, and laboratory findings between lupus and COVID-19 pneumonitis are outlined. In conclusion, patients with lupus may be affected by COVID-19 despite the administration of hydroxychloroquine. The administration of steroids may have a beneficial effect on mitigating both the flare of SLE and the COVID-19 associated hyperinflammation.
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页数:4
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