Synthesis of fused chromenes by the indium(III)-catalyzed cascade hydroarylation/cycloisomerization reactions of polyyne-type aryl propargyl ethers

被引：22

作者：

Alonso-Maranon, Lorena

Sarandeses, Luis A.

Montserrat Martinez, M. ^{[1
,2
]}

Perez Sestelo, Jose ^{[1
,2
]}

机构：

[1] Univ A Coruna, CICA, E-15071 La Coruna, Spain

[2] Univ A Coruna, Dept Quim, E-15071 La Coruna, Spain

来源：

ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 15期

关键词：

CATALYZED INTRAMOLECULAR HYDROARYLATION; RING-CLOSURE; ORGANIC-SYNTHESIS; TANDEM CATALYSIS; BALDWIN RULES; PI-ACTIVATION; ALKYNES; CYCLIZATION; GOLD; CYCLOISOMERIZATION;

D O I：

10.1039/c8qo00457a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fused 2H-chromenes are prepared by the cascade hydroarylation/cycloisomerization reactions of polyyne-type aryl propargyl ethers using indium(III) catalysis. The transformation proceeds with 6-endo-dig regioselectivity using InBr3 (5 mol%). The method can be extended to triynes allowing the formation of three bonds in one pot. Indium(III) also catalyzes the hydroamination/hydroarylation cascade reaction of o-aryldiynyl anilines to form fused carbazoles.

引用

收藏

页码：2308 / 2312

页数：5

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