Inhibitory MHC class I receptors on γδ T cells in tumour immunity and autoimmunity

被引：53

作者：

Fisch, P ^{[1
]}

Moris, A

Rammensee, HG

Handgretinger, R

机构：

[1] Univ Freiburg, Dept Pathol, D-79104 Freiburg, Germany

[2] Univ Tubingen, Dept Immunol, D-72076 Tubingen, Germany

[3] Univ Tubingen, Childrens Hosp, Dept Pediat, D-72076 Tubingen, Germany

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 04期

关键词：

D O I：

10.1016/S0167-5699(99)01576-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The function of gamma delta T cells is still subject to speculation. The V gamma 9/V delta 2 T-cell receptor of the major gamma delta T-cell subset in human blood recognizes bacterial phosphoantigens and pearly characterized ligands expressed by B-cell lymphomas. Recent data on the expression and function of natural killer inhibitory receptors on human gamma delta T cells have led to the provocative hypothesis that ya T-cell subsets expanded in vivo may attack tumour cells or induce autoimmunity.

引用

页码：187 / 191

页数：5

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