Treatment of Diabetes in Older Adults: An Endocrine Society Clinical Practice Guideline

被引：316
作者：
LeRoith, Derek [1 ]
Biessels, Geert Jan [2 ]
Braithwaite, Susan S. [3 ,4 ]
Casanueva, Felipe F. [5 ]
Draznin, Boris [6 ]
Halter, Jeffrey B. [7 ,8 ]
Hirsch, Irl B. [9 ]
McDonnell, Marie E. [10 ]
Molitch, Mark E. [11 ]
Murad, M. Hassan [12 ]
Sinclair, Alan J. [13 ]
机构：
[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[2] Univ Med Ctr Utrecht, NL-3584 CX Utrecht, Netherlands
[3] Presence St Francis Hosp, Evanston, IL 60202 USA
[4] Presence St Joseph Hosp, Chicago, IL 60657 USA
[5] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr, Complejo Hosp Univ Santiago, Santiago De Compostela 15782, Spain
[6] Univ Colorado Denver, Anschutz Med Campus, Aurora, CO 80045 USA
[7] Univ Michigan, Ann Arbor, MI 48109 USA
[8] Natl Univ Singapore, Singapore 119077, Singapore
[9] Univ Washington, Med Ctr Roosevelt, Seattle, WA 98105 USA
[10] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA
[11] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[12] Mayo Clin, Div Prevent Med, Rochester, MN 55905 USA
[13] Kings Coll London, London SE1 9NH, England
来源：
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2019年 / 104卷 / 05期
关键词：
LOWER-EXTREMITY AMPUTATION; BLOOD-PRESSURE CONTROL; LONG-TERM-CARE; INTENSIVE GLYCEMIC CONTROL; LIFE-STYLE INTERVENTION; CORONARY-HEART-DISEASE; ALL-CAUSE MORTALITY; CONVERTING-ENZYME-INHIBITION; LEFT-VENTRICULAR DYSFUNCTION; CONTROL-CARDIOVASCULAR-RISK;
D O I：
10.1210/jc.2019-00198
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: The objective is to formulate clinical practice guidelines for the treatment of diabetes in older adults. Conclusions: Diabetes, particularly type 2, is becoming more prevalent in the general population, especially in individuals over the age of 65 years. The underlying pathophysiology of the disease in these patients is exacerbated by the direct effects of aging on metabolic regulation. Similarly, aging effects interact with diabetes to accelerate the progression of many common diabetes complications. Each section in this guideline covers all aspects of the etiology and available evidence, primarily from controlled trials, on therapeutic options and outcomes in this population. The goal is to give guidance to practicing health care providers that will benefit patients with diabetes (both type 1 and type 2), paying particular attention to avoiding unnecessary and/or harmful adverse effects.
引用
收藏
页码：1520 / 1574
页数：55
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