Oxidative bromination of activated aromatic compounds using aqueous nitric acid as an oxidant

被引：36

作者：

Joshi, AV

Baidossi, M

Mukhopadhyay, S

Sasson, Y ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Casali Inst Appl Chem, IL-91904 Jerusalem, Israel

[2] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2004年 / 8卷 / 04期

关键词：

D O I：

10.1021/op030055w

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Oxidative bromination of activated aromatic compounds using alkali metal bromide salts and aqueous nitric acid to the corresponding bromo-derivatives is achieved in a liquid-liquid, two-phase system under ambient conditions. Nitric acid offers a dual function of an oxidant as well as a proton donor, which is essential for oxidative bromination using metal bromide salts. Bromination as well as chlorination could be accomplished with this simple system.

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页码：568 / 570

页数：3

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