Efficacy of Selective Arterial Embolisation for the Treatment of Life-Threatening Post-Partum Haemorrhage in a Large Population

被引:58
作者
Touboul, Cyril [1 ]
Badiou, Wassim [1 ]
Saada, Julien [1 ]
Pelage, Jean-Pierre [2 ]
Payen, Didier [3 ]
Vicaut, Eric [4 ]
Jacob, Denis [1 ]
Rafii, Arash [5 ]
机构
[1] Hop Lariboisiere, AP HP, Dept Obstet & Gynaecol, F-75475 Paris, France
[2] Hop Lariboisiere, AP HP, Dept Vasc Imaging, Paris, France
[3] Hop Lariboisiere, AP HP, Dept Anaesthesiol & Critical Care, Paris, France
[4] Hop Lariboisiere, AP HP, Dept Nuclear Med, Paris, France
[5] Weill Cornell Med Coll, Dept Genet Med & Obstet & Gynecol, Paris, France
关键词
D O I
10.1371/journal.pone.0003819
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background: The objective of this study was to assess efficacy and determine the optimal indication of selective arterial embolisation (SAE) in patients with life-threatening post-partum haemorrhage (PPH). Methodology/Principal Findings: One hundred and two patients with PPH underwent SAE and were included from January 1998 to January 2002 in our university care center. Embolisation was considered effective when no other surgical procedure was required. Univariate and multivariate statistical analysis were performed. SAE was effective for 73 patients (71.5%), while 29 required surgical procedures. SAE was effective in 88.6% of women with uterine atony that was associated with positive outcome (OR 4.13, 1.35-12.60), whereas caesarean deliveries (OR 0.16, 0.04-0.5) and haemodynamic shock (OR 0.21, 0.07-0.60) were associated with high failure rates, 47.6% and 39.1%, respectively. Conclusions/Significance: Success rate for SAE observed in a large population is lower than previously reported. It is most likely to succeed for uterine atony but not recommended in case of haemodynamic shock or after caesarean section.
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