Synthesis of 2-(aryl methylene)-(1H)-indane-1,3-(2H)-diones as potential fungicidal and bactericidal agents

被引:0
作者
Meena, S. [1 ]
Shankar, D. [1 ]
Ramseshu, K. V. [1 ]
Giles, D. [1 ]
Prakash, M. S. [1 ]
Venkataraman, S. [1 ]
机构
[1] KM Coll Pharm, Dept Pharmaceut Chem, Madurai 625107, Tamil Nadu, India
来源
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2006年 / 45卷 / 06期
关键词
indanediones; indane-1,3-dione; aldehyde derivatives; synthesis; antifungal activity; antibacterial activity;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of diethyl phthalate 1 and ethyl acetate 2 in the presence of sodium metal and ethanol affords indane-1, 3-dione 3, which have been substituted at C-2 position with different aromatic aldehydes 4, to yield their respective aryl derivatives of indane-1,3-dione 5a-h. These derivatives are evaluated for their antifungal and antibacterial activity. The structures of all the compounds are determined by IR, H-1 NMR and mass spectrometry.
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页码:1572 / 1575
页数:4
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