Rhabdomyoblastic differentiation in malignant melanoma in adults: Report of 2 cases

被引：27
作者：
Gharpuray-Pandit, Deepa
Coyne, John
Eyden, Brian [1 ]
Banerjee, S. Sankar
机构：
[1] Christie Hosp NHS Trust, Dept Histopathol, Manchester M20 4BX, Lancs, England
[2] Wythenshawe Hosp, Manchester M23 9LT, Lancs, England
来源：
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2007年 / 15卷 / 01期
关键词：
melanoma; rhabdomyoblastic differentiation; immunohistochemistry; electron microscopy;
D O I：
10.1177/1066896906295775
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Two cases of malignant melanoma are reported in adults exhibiting rhabdomyoblastic differentiation to alert pathologists to this rare variant of malignant melanoma. One of the cases presented as a metastasis in a submandibular lymph node, and the other was a primary skin melanoma. There are only a few published reports on melanocytic tumors with rhabdomyoblastic differentiation, mainly occurring in giant congenital nevi. Both cases reported here were confirmed by immunohistochemistry. Both cases were also studied by electron microscopy, and one showed distinctive ultrastructural features of striated muscle.
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页码：20 / 25
页数：6
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