The Economic Burden Attributable to a Child's Inpatient Admission for Diarrheal Disease in Rwanda

被引:31
作者
Ngabo, Fidele [1 ,2 ]
Mvundura, Mercy [3 ]
Gazley, Lauren [4 ]
Gatera, Maurice [2 ]
Rugambwa, Celse [5 ]
Kayonga, Eugene [2 ]
Tuyishime, Yvette [2 ]
Niyibaho, Jeanne [2 ]
Mwenda, Jason M. [6 ]
Donnen, Philippe [1 ]
Lepage, Philippe [7 ]
Binagwaho, Agnes [8 ,9 ,10 ]
Atherly, Deborah [4 ]
机构
[1] Univ Libre Bruxelles, Ecole Sante Publ, Brussels, Belgium
[2] Minist Hlth, Rwanda Biomed Ctr, Kigali, Rwanda
[3] PATH, Devices & Tools Global Program, Seattle, WA 98121 USA
[4] PATH, Vaccine Access & Delivery Global Program, Seattle, WA 98121 USA
[5] WHO, Rwanda Country Off, Kigali, Rwanda
[6] WHO, Reg Off Africa, Brazzaville, Rep Congo
[7] Univ Libre Bruxelles, Hop Univ Enfants Reine Fabiola, Brussels, Belgium
[8] Minist Hlth, Kigali, Rwanda
[9] Harvard Univ, Sch Med, Boston, MA USA
[10] Dartmouth, Geisel Sch Med, Hanover, NH USA
关键词
ROTAVIRUS VACCINATION; COST-EFFECTIVENESS; HEALTH; IMPACT; COUNTRIES; CARE; GASTROENTERITIS;
D O I
10.1371/journal.pone.0149805
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Diarrhea is one of the leading causes of childhood morbidity and mortality. Hospitalization for diarrhea can pose a significant burden to health systems and households. The objective of this study was to estimate the economic burden attributable to hospitalization for diarrhea among children less than five years old in Rwanda. These data can be used by decisionmakers to assess the impact of interventions that reduce diarrhea morbidity, including rotavirus vaccine introduction. Methods This was a prospective costing study where medical records and hospital bills for children admitted with diarrhea at three hospitals were collected to estimate resource use and costs. Hospital length of stay was calculated from medical records. Costs incurred during the hospitalization were abstracted from the hospital bills. Interviews with the child's caregivers provided data to estimate household costs which included transport costs and lost income. The portion of medical costs borne by insurance and household were reported separately. Annual economic burden before and after rotavirus vaccine introduction was estimated by multiplying the reported number of diarrhea hospitalizations in public health centers and district hospitals by the estimated economic burden per hospitalization. All costs are presented in 2014 US$. Results Costs for 203 children were analyzed. Approximately 93% of the children had health insurance coverage. Average hospital length of stay was 5.3 +/- 3.9 days. Average medical costs for each child for the illness resulting in a hospitalization were $44.22 +/- $23.74 and the total economic burden was $101, of which 65% was borne by the household. For households in the lowest income quintile, the household costs were 110% of their monthly income. The annual economic burden to Rwanda attributable to diarrhea hospitalizations ranged from $1.3 million to $1.7 million before rotavirus vaccine introduction. Conclusion Households often bear the largest share of the economic burden attributable to diarrhea hospitalization and the burden can be substantial, especially for households in the lowest income quintile.
引用
收藏
页数:16
相关论文
共 22 条
[1]   Hospital Health Care Cost of Diarrheal Disease in Northern Ghana [J].
Aikins, Moses ;
Armah, George ;
Akazili, James ;
Hodgson, Abraham .
JOURNAL OF INFECTIOUS DISEASES, 2010, 202 :S126-S130
[2]   Anticipating rotavirus vaccines - a pre-vaccine assessment of incidence and economic burden of rotavirus hospitalizations among children < 5 year of age in Libya, 2012-13 [J].
Alkoshi, Salem ;
Leshem, Eyal ;
Parashar, Umesh D. ;
Dahlui, Maznah .
BMC PUBLIC HEALTH, 2015, 15
[3]   Projected health and economic impact of rotavirus vaccination in GAVI-eligible countries: 2011-2030 [J].
Atherly, Deborah E. ;
Lewis, Kristen D. C. ;
Tate, Jacqueline ;
Parashar, Umesh D. ;
Rheingans, Richard D. .
VACCINE, 2012, 30 :A7-A14
[4]   The burden of pediatric diarrhea: a cross-sectional study of incurred costs and perceptions of cost among Bolivian families [J].
Burke, Rachel M. ;
Rebolledo, Paulina A. ;
Embrey, Sally R. ;
Wagner, Laura Danielle ;
Cowden, Carter L. ;
Kelly, Fiona M. ;
Smith, Emily R. ;
Iniguez, Volga ;
Leon, Juan S. .
BMC PUBLIC HEALTH, 2013, 13
[5]   Health care costs of diarrheal disease and estimates of the cost-effectiveness of rotavirus vaccination in Vietnam [J].
Fischer, TK ;
Anh, DD ;
Antil, L ;
Cat, NDL ;
Kilgore, PE ;
Thiem, VD ;
Rheingans, R ;
Tho, LH ;
Glass, RI ;
Bresee, JS .
JOURNAL OF INFECTIOUS DISEASES, 2005, 192 (10) :1720-1726
[6]   Costs of community-acquired pediatric rotavirus gastroenteritis in 7 European countries: The REVEAL study [J].
Giaquinto, Carlo ;
Van Damme, Pierre ;
Huet, Frederic ;
Gothefors, Leif ;
Van der Wielen, Marie .
JOURNAL OF INFECTIOUS DISEASES, 2007, 195 :S36-S44
[7]   Hospital-based study of the economic burden associated with rotavirus diarrhea in eastern China [J].
Jin, Hui ;
Wang, Bei ;
Fang, Zhaoyin ;
Duan, Zhaojun ;
Gao, Qian ;
Liu, Na ;
Zhang, Lijie ;
Qian, Yuan ;
Gong, Sitang ;
Zhu, Qirong ;
Shen, Xiaona ;
Wu, Qingbin .
VACCINE, 2011, 29 (44) :7801-7806
[8]   Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000 [J].
Liu, Li ;
Johnson, Hope L. ;
Cousens, Simon ;
Perin, Jamie ;
Scott, Susana ;
Lawn, Joy E. ;
Rudan, Igor ;
Campbell, Harry ;
Cibulskis, Richard ;
Li, Mengying ;
Mathers, Colin ;
Black, Robert E. .
LANCET, 2012, 379 (9832) :2151-2161
[9]   The Economic Burden of Diarrheal Disease in a Tertiary Level Hospital, Gauteng, South Africa [J].
MacIntyre, Una E. ;
de Villiers, Francois P. R. .
JOURNAL OF INFECTIOUS DISEASES, 2010, 202 :S116-S125
[10]   Can Routinely Collected National Data on Childhood Morbidity and Mortality from Diarrhea be Used to Monitor Health Impact of Rotavirus Vaccination in Africa? Examination of Pre-Vaccine Baseline Data from Rwanda [J].
Ngabo, Fidele ;
Gatera, Maurice ;
Karema, Corrine ;
Donnen, Philippe ;
Lepage, Philippe ;
Parashar, Umesh D. ;
Tate, Jacqueline E. ;
Mwenda, Jason M. ;
Rugambwa, Celse ;
Binagwaho, Agnes .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2014, 33 :S89-S93