High rate of monoclonal gammopathy among immunocompetent subjects with primary cytomegalovirus infection

被引:11
作者
Bühler, S
Laitinen, K
Holthöfer, H
Järvinen, A
Schauman, KO
Hedman, K
机构
[1] Univ Helsinki, Cent Hosp, Diagnost Lab, Dept Virol, FIN-00029 Huch, Finland
[2] Univ Helsinki, Cent Hosp, Dept Internal Med, FIN-00029 Huch, Finland
[3] Univ Helsinki, Cent Hosp, Dept Bacteriol & Immunol, FIN-00029 Huch, Finland
[4] Helsinki Municipal Hosp, Dept Clin Chem, Helsinki, Finland
[5] Helsinki Municipal Hosp, Haartman Inst, Helsinki, Finland
关键词
D O I
10.1086/344465
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Serum samples from immunocompetent adults with primary cytomegalovirus (CMV) or Epstein-Barr virus (EBV) infection and from solid-organ or bone marrow transplant recipients with primary CMV infection were examined for paraproteins. Several immunocompetent patients with CMV infection but none with EBV infection presented with an M component, which implies that the M component connects CMV infection to a risk of B cell malignancy.
引用
收藏
页码:1430 / 1433
页数:4
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