Gut microbiota modulate host immune cells in cancer development and growth

被引:20
作者
Erdman, Susan E. [1 ]
Poutahidis, Theofilos [1 ,2 ]
机构
[1] MIT, Div Comparat Med, Cambridge, MA 02139 USA
[2] Aristotle Univ Thessaloniki, Coll Vet Med, Dept Pathol, Thessaloniki, Greece
基金
美国国家卫生研究院;
关键词
Bacteria; Neutrophil; Lymphocyte; Homeostasis; Health; Hygiene; Thymus; REGULATORY T-CELLS; NEUTROPHIL HOMEOSTASIS; INDUCED INFLAMMATION; IFN-GAMMA; OXYTOCIN; BACTERIA; MECHANISMS; TOLERANCE; SYSTEM; HEALTH;
D O I
10.1016/j.freeradbiomed.2016.11.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Emerging evidence shows that microbe interactions with the host immune system impact diverse aspects of cancer development and treatment. As a result, exciting new opportunities exist for engineering diets and microbe cocktails to lower cancer risks with fewer adverse clinical effects than traditional strategies. Microbe based therapies may ultimately be used to reinforce host immune balance and extinguish cancer for generations to come.
引用
收藏
页码:28 / 34
页数:7
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