Algal transformation of hydrocortisone by the cyanobacterium Nostoc ellipsosporum

被引：8
|
作者：
Ghasemi, Y.
Yazdi, M. Tabatabaei
Dehshahri, A.
Niknahad, H.
Shokravi, S.
Amini, M.
Ghasemian, A.
Faramarzi, M. A.
机构：
[1] Shiraz Univ Med Sci, Dept Pharmacognosy, Tehran, Iran
[2] Shiraz Univ Med Sci, Dept Pharmaceut Biotechnol, Tehran, Iran
[3] Shiraz Univ Med Sci, Dept Pharmacol & Toxicol, Fac Pharm, Tehran, Iran
[4] Univ Tehran Med Sci, Dept Med Chem, Fac Pharm, Tehran, Iran
[5] Shaheed Beheshti Univ Med Sci, Dept Biol, Inst Appl Sci, Iranian Ctr Culture & Educ, Tehran, Iran
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 06期
关键词：
biotransformation; hydrocortisone; microalgae; Nostoc ellipsosporum;
D O I：
10.1007/s10600-006-0257-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The potential of Nostoc ellipsosporum for biotransformation of hydrocortisone was studied. The microorganism was isolated during a screening program from soil samples collected from the paddy fields in the north of Iran and had not been previously examined for this purpose. The biotransformation yielded 11 beta,17 alpha,20 beta, 21-tetrahydroxypregn-4-en-3-one and 11 beta-hydroxyandrost-4-ene-3,17-dione. Both of the metabolites were purified chromatographically and characterized using instrumental analyses.
引用
收藏
页码：702 / 705
页数：4
相关论文
共 50 条
  • [1] Algal transformation of hydrocortisone by the cyanobacterium Nostoc ellipsosporum
    Y. Ghasemi
    M. Tabatabaei Yazdi
    A. Dehshahri
    H. Niknahad
    S. Shokravi
    M. Amini
    A. Ghasemian
    M. A. Faramarzi
    Chemistry of Natural Compounds, 2006, 42 : 702 - 705
  • [2] TRANSFORMATION IN THE CYANOBACTERIUM NOSTOC
    TRIPATHI, AK
    KUMAR, HD
    BIOLOGISCHES ZENTRALBLATT, 1985, 104 (03): : 239 - 243
  • [3] Antioxidative responses of Nostoc ellipsosporum and Nostoc piscinale to salt stress
    Maryam Rezayian
    Vahid Niknam
    Mohammad Ali Faramarzi
    Journal of Applied Phycology, 2019, 31 : 157 - 169
  • [4] Antioxidative responses of Nostoc ellipsosporum and Nostoc piscinale to salt stress
    Rezayian, Maryam
    Niknam, Vahid
    Faramarzi, Mohammad Ali
    JOURNAL OF APPLIED PHYCOLOGY, 2019, 31 (01) : 157 - 169
  • [5] Modeling the effects of light wavelength on the growth of Nostoc ellipsosporum
    Ortiz-Moreno, Martha-Lucia
    Cardenas-Poblador, Jaleydi
    Agredo, Julian
    Solarte-Murillo, Laura-Vanessa
    UNIVERSITAS SCIENTIARUM, 2020, 25 (01) : 113 - 148
  • [6] GENETIC-TRANSFORMATION OF GLUTAMINE AUXOTROPHY TO PROTOTROPHY IN THE CYANOBACTERIUM NOSTOC-MUSCORUM
    VERMA, SK
    SINGH, AK
    KATIYAR, S
    SINGH, HN
    ARCHIVES OF MICROBIOLOGY, 1990, 154 (04) : 414 - 416
  • [7] Toxicity evaluation of iron oxide nanoparticles to freshwater cyanobacteria Nostoc ellipsosporum
    Kumar, Mukesh
    Seth, Kunal
    Choudhary, Sunita
    Kumawat, Geetanjali
    Nigam, Subhasha
    Joshi, Garima
    Saharan, Vinod
    Meena, Mukesh
    Gupta, Amit Kumar
    Harish
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 30 (19) : 55742 - 55755
  • [8] Toxicity evaluation of iron oxide nanoparticles to freshwater cyanobacteria Nostoc ellipsosporum
    Mukesh Kumar
    Kunal Seth
    Sunita Choudhary
    Geetanjali Kumawat
    Subhasha Nigam
    Garima Joshi
    Vinod Saharan
    Mukesh Meena
    Amit Kumar Gupta
    Environmental Science and Pollution Research, 2023, 30 : 55742 - 55755
  • [9] DNA-MEDIATED TRANSFORMATION IN NOSTOC-MUSCORUM, A NITROGEN-FIXING CYANOBACTERIUM
    TREHAN, K
    SINHA, U
    AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, 1982, 35 (05) : 573 - 577
  • [10] Cellular differentiation in the cyanobacterium Nostoc punctiforme
    Meeks, JC
    Campbell, EL
    Summers, ML
    Wong, FC
    ARCHIVES OF MICROBIOLOGY, 2002, 178 (06) : 395 - 403
12345