Current aspects of pulmonary arterial hypertension and therapeutics

被引:1
作者
Li, Xianchi [1 ]
Liu, Yuanyuang [1 ]
Zhang, Peiying [1 ]
机构
[1] Xuzhou Cent Hosp, Xuzhou, Peoples R China
来源
MINERVA CARDIOANGIOLOGICA | 2017年 / 65卷 / 02期
关键词
Hypertension; pulmonary; Therapeutics; Adrenergic beta-antagonists; RIGHT-VENTRICULAR FUNCTION; CALCIUM-CHANNEL BLOCKERS; LONG-TERM RESPONSE; SIGNALING CONTRIBUTES; AEROBIC EXERCISE; SURVIVAL; PROSTACYCLIN; MANAGEMENT; PHYSIOLOGY; DISEASE;
D O I
10.23736/S0026-4725.16.04266-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The pulmonary arterial hypertension (PAH) patients have high rate of mortality due to right ventricle (or ventricular) (RV) failures. A lot of research work is being carried out in the area, however no treatment is available that could contrast the rise in mortality rates in PAH patients. beta 1-adrenoceptor blockers (beta-blockers, BB) reduced mortality in left heart failure, but they do not explored much at clinical level. Recent studies suggest beta-blockers might be beneficial in PAH; however the mechanisms remain unknown. The present review article would put light on all these aspects of PAH along with latest ways for the management of PAH.
引用
收藏
页码:173 / 178
页数:6
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