Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus

被引：30
作者：
O'Neill, S. G.
Woldman, S. [2 ]
Bailliard, F. [3 ,4 ]
Norman, W. [3 ,4 ]
McEwan, J. [2 ]
Isenberg, D. A.
Taylor, A. M. [3 ,4 ]
Rahman, A. [1 ]
机构：
[1] UCL, Div Med, Ctr Rheumatol Res, Dept Med, London W1T 4JF, England
[2] Univ Coll London Hosp, Heart Hosp, London, England
[3] UCL, Cardiothorac Unit, Inst Child Hlth, Ctr Cardiovasc MR, London W1T 4JF, England
[4] Great Ormond St Hosp Sick Children, London WC1N 3JH, England
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2009年 / 68卷 / 09期
关键词：
DISEASE; ATHEROSCLEROSIS; WOMEN; CLASSIFICATION; CRITERIA; COHORT; HEART; AGE;
D O I：
10.1136/ard.2008.098053
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objectives: To delineate the cardiac magnetic resonance (MR) appearances of cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE), in comparison with transthoracic echocardiographs. Methods: Cardiac MR was performed on 22 patients with SLE-11 with previous CVD and 11 matched controls-using late gadolinium contrast enhancement (LGE) to identify areas of myocardial scarring; Transthoracic echocardiography (TTE) was performed on the same day. Results: Twenty female and two male patients participated. LGE was seen in 5/11 subjects in the CVD group (4/5 with previous myocardial infarction) and 1/11 in the control group. TTE detected myocardial abnormalities in 2/6 patients with LGE. Conclusion: The cardiac MR appearance of CVD in these patients with SLE was suggestive of coronary disease, rather than cumulative inflammatory muscle damage. Cardiac MR detected more abnormalities than TTE. Further studies of cardiac MR in patients with SLE are warranted to investigate these preliminary findings.
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收藏
页码：1478 / 1481
页数：4
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