Dengue infection: neurological manifestations and cerebrospinal fluid (CSF) analysis

被引:86
作者
Soares, C. N.
Faria, L. C.
Peralta, J. M.
de Freitas, M. R. G.
Puccioni-Sohler, M.
机构
[1] Univ Fed Fluminense, Neurol Serv, HUAP, Niteroi, RJ, Brazil
[2] CSF, Neurolife Lab, Rio De Janeiro, Brazil
[3] UFRG, HUCFF, CSF Lab, Clin Pathol Serv, Rio De Janeiro, Brazil
[4] UFRJ, CCS, Inst Microbiol, Rio De Janeiro, Brazil
[5] Univ Fed Estado Rio de Janeiro, Neurol Serv, HUGG, UNIRIO, Rio De Janeiro, Brazil
关键词
dengue infection; neurological manifestations; CSF; viral encephalitis; myelitis and Guillain-Barre syndrome;
D O I
10.1016/j.jns.2006.05.068
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barre syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:19 / 24
页数:6
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