Highly Sensitive Metamaterial Biosensor for Cancer Early Detection

被引：79

作者：

Azab, Mohammad Y. ^{[1
]}

Hameed, Mohamed Farhat O. ^{[1
,2
]}

Nasr, Abed M. ^{[1
]}

Obayya, S. S. A. ^{[2
]}

机构：

[1] Mansoura Univ, Fac Engn, Math & Engn Phys Dept, Mansoura 35516, Egypt

[2] Zewail City Sci & Technol, Ctr Photon & Smart Mat, Giza 12578, Egypt

来源：

IEEE SENSORS JOURNAL | 2021年 / 21卷 / 06期

关键词：

Metamaterials; Absorption; Sensors; Sensitivity; Biosensors; Cancer; Resonant frequency; Metamaterial; absorber; biosensor; cancer detection; and terahertz;

D O I：

10.1109/JSEN.2021.3051075

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A novel design of metamaterial biosensor for cancer early detection is proposed and analyzed. The suggested structure is based on two loops of hexagonal gold layers on a polyamide substrate. High field confinement is obtained in the sensing region with high absorption of 0.999 and high quality factor of 11.33 at f 3.15 THz. The resonance frequency is sensitive to the sample refractive index variation. Therefore, high average sensitivity of 1649.8 GHz/RIU is achieved for cancer early detection through basal cell, breast cell, bervical cell, jurkat, MCF-7, and PC12. Further, high linear performance is obtained with good robustness against fabrication imperfection. The analysis is carried out using full vectorial finite element method.

引用

页码：7748 / 7755

页数：8

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