Highly Sensitive Metamaterial Biosensor for Cancer Early Detection

被引：80
作者：
Azab, Mohammad Y. [1 ]
Hameed, Mohamed Farhat O. [1 ,2 ]
Nasr, Abed M. [1 ]
Obayya, S. S. A. [2 ]
机构：
[1] Mansoura Univ, Fac Engn, Math & Engn Phys Dept, Mansoura 35516, Egypt
[2] Zewail City Sci & Technol, Ctr Photon & Smart Mat, Giza 12578, Egypt
来源：
IEEE SENSORS JOURNAL | 2021年 / 21卷 / 06期
关键词：
Metamaterials; Absorption; Sensors; Sensitivity; Biosensors; Cancer; Resonant frequency; Metamaterial; absorber; biosensor; cancer detection; and terahertz;
D O I：
10.1109/JSEN.2021.3051075
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A novel design of metamaterial biosensor for cancer early detection is proposed and analyzed. The suggested structure is based on two loops of hexagonal gold layers on a polyamide substrate. High field confinement is obtained in the sensing region with high absorption of 0.999 and high quality factor of 11.33 at f 3.15 THz. The resonance frequency is sensitive to the sample refractive index variation. Therefore, high average sensitivity of 1649.8 GHz/RIU is achieved for cancer early detection through basal cell, breast cell, bervical cell, jurkat, MCF-7, and PC12. Further, high linear performance is obtained with good robustness against fabrication imperfection. The analysis is carried out using full vectorial finite element method.
引用
收藏
页码：7748 / 7755
页数：8
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