Attitudes and practices of pediatric oncology providers regarding fertility issues

被引:108
作者
Goodwin, Tress
Oosterhuis, B. Elizabeth
Kiernan, Michaela
Hudson, Melissa A.
Dahl, Gary V.
机构
[1] Stanford Univ, Med Ctr, Div Pediat Hematol Oncol, Stanford, CA 94305 USA
[2] Stanford Prevent Res Ctr, Stanford, CA USA
[3] St Jude Childrens Hosp, Memphis, TN 38105 USA
关键词
fertility; health care provider; late effects; pediatric oncology/hematology;
D O I
10.1002/pbc.20814
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose. Given the higher survival rates of childhood cancer, health care providers must be aware of the side effects of cancer therapies to educate patients and provide appropriate interventions to reduce cancer-related morbidity. To understand the current practices and attitudes in a pediatric hematology/oncology clinic, health care providers were surveyed regarding fertility issues pertinent to their patient care. Participants and Instruments. In this study, 93.8% (30/32) health care providers in one pediatric hematology/oncology department completed a 44-item survey assessing knowledge, current practices, obstacles to current practices, perceptions of patient differences, and improvements to future practice. Results. The majority of health care providers were aware of the adverse effects of alkylating agents (90.7%) and of abdominal and pelvic radiation (100.0%) on fertility. However, only half were aware of gender differences in gonadotoxicity (50.0%) or knowledgeable of current research and technology in fertility preservation (53.3%). While only 34.6% of providers currently consulted with specialists, nearly all (92.8%) indicated a desire to do so in the future, but 64.3% indicated difficulties in finding proper facilities and specialists for their patients. Almost all (96.6%) agreed that providers and patient families need more information regarding the effects of cancer therapy on fertility. Conclusions. Surveyed pediatric oncology providers considered fertility to be an important issue for childhood cancer patients and desired more resources regarding effects on fertility and fertility preservation. Greater communication needs to be established between pediatric oncology providers and specialists in reproductive medicine and endocrinology to ensure adequate professional collaboration and patient referrals.
引用
收藏
页码:80 / 85
页数:6
相关论文
共 19 条
  • [1] Genetic disease in offspring of long-term survivors of childhood and adolescent cancer
    Byrne, J
    Rasmussen, SA
    Steinhorn, SC
    Connelly, RR
    Myers, MH
    Lynch, CF
    Flannery, J
    Austin, DF
    Holmes, FF
    Holmes, GE
    Strong, LC
    Mulvihill, JJ
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 62 (01) : 45 - 52
  • [2] Livebirth after orthotopic transplantation of cryopreserved ovarian tissue
    Donnez, J
    Dolmans, MM
    Demylle, D
    Jadoul, P
    Pirard, C
    Squifflet, J
    Martinez-Madrid, B
    Van Langendonckt, A
    [J]. LANCET, 2004, 364 (9443) : 1405 - 1410
  • [3] Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy
    Meirow, D
    Levron, J
    Eldar-Geva, T
    Hardan, I
    Fridman, E
    Zalel, Y
    Schiff, E
    Dor, J
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (03) : 318 - 321
  • [4] Meistrich Marvin L., 1997, P2758
  • [5] NICHOLSON HS, 1993, CANCER-AM CANCER SOC, V71, P3392, DOI 10.1002/1097-0142(19930515)71:10+<3392::AID-CNCR2820711743>3.0.CO
  • [6] 2-F
  • [7] Ovarian function after transplantation of frozen, banked autologous ovarian tissue.
    Oktay, K
    Karlikaya, G
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (25) : 1919 - 1919
  • [8] Embryo development after heterotopic transplantation of cryopreserved ovarian tissue
    Oktay, K
    Buyuk, E
    Veeck, L
    Zaninovic, N
    Xu, KP
    Takeuchi, T
    Opsahl, M
    Rosenwaks, Z
    [J]. LANCET, 2004, 363 (9412) : 837 - 840
  • [9] Pizzo PA, 2005, PRINCIPLES PRACTICE
  • [10] Ries L, 2001, SEER CANC STAT REV 1