A New Porous Reaction Layer for Developing Addressable Molecular Libraries

被引：23

作者：

Hu, Libo ^{[1
]}

Bartels, Jennifer L. ^{[1
]}

Bartels, Jeremy W. ^{[1
]}

Maurer, Karl ^{[2
]}

Moeller, Kevin D. ^{[1
]}

机构：

[1] Washington Univ, Dept Chem, St Louis, MO 63130 USA

[2] CombiMatrix Corp, Mukilteo, WA 98275 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 46期

基金：

美国国家科学基金会;

关键词：

BIOACTIVE HYDROGEL LAYERS; MICROELECTRODE ARRAYS; ELECTRODES; SURFACES; CELLS; ACID;

D O I：

10.1021/ja907000m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new diblock copolymer-derived porous reaction Layer for microelectrode arrays has I been tested for its stability and its compatibility with both site-selective synthesis and electrochemical signaling experiments. The diblock copolymer consisted of a cinnamoyl-substituted polymethacrylate block for attachment to the surface of the array and a bromo-substituted polystyrene block for selective functionalization of the surface proximal to microelectrodes in the array. Site-selective Suzuki, Heck, and Cu(I)-coupling reactions were all performed on the new reaction layer along with electrochemical impedance studies.

引用

收藏

页码：16638 / +

页数：4

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