A New Porous Reaction Layer for Developing Addressable Molecular Libraries

被引:23
作者
Hu, Libo [1 ]
Bartels, Jennifer L. [1 ]
Bartels, Jeremy W. [1 ]
Maurer, Karl [2 ]
Moeller, Kevin D. [1 ]
机构
[1] Washington Univ, Dept Chem, St Louis, MO 63130 USA
[2] CombiMatrix Corp, Mukilteo, WA 98275 USA
基金
美国国家科学基金会;
关键词
BIOACTIVE HYDROGEL LAYERS; MICROELECTRODE ARRAYS; ELECTRODES; SURFACES; CELLS; ACID;
D O I
10.1021/ja907000m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new diblock copolymer-derived porous reaction Layer for microelectrode arrays has I been tested for its stability and its compatibility with both site-selective synthesis and electrochemical signaling experiments. The diblock copolymer consisted of a cinnamoyl-substituted polymethacrylate block for attachment to the surface of the array and a bromo-substituted polystyrene block for selective functionalization of the surface proximal to microelectrodes in the array. Site-selective Suzuki, Heck, and Cu(I)-coupling reactions were all performed on the new reaction layer along with electrochemical impedance studies.
引用
收藏
页码:16638 / +
页数:4
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