Protein complexes in transport vesicle targeting

被引:175
作者
Guo, W
Sacher, M
Barrowman, J
Ferro-Novick, S
Novick, P
机构
[1] Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA
关键词
D O I
10.1016/S0962-8924(00)01754-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The transport of material between membrane-bounded organelles in eukaryotic cells requires the accurate delivery of different Classes of carrier vesicles to specific target compartments. Recent studies indicate that different targeting reactions involve distinct protein complexes that act to mark the target organelle for incoming vesicles. This review focuses on the proteins and protein complexes that have been implicated in various targeting reactions.
引用
收藏
页码:251 / 255
页数:5
相关论文
共 60 条
[1]   THE GTP-BINDING PROTEIN YPT1 IS REQUIRED FOR TRANSPORT INVITRO - THE GOLGI-APPARATUS IS DEFECTIVE IN YPT1 MUTANTS [J].
BACON, RA ;
SALMINEN, A ;
RUOHOLA, H ;
NOVICK, P ;
FERRONOVICK, S .
JOURNAL OF CELL BIOLOGY, 1989, 109 (03) :1015-1022
[2]   Coupled ER to Golgi transport reconstituted with purified cytosolic proteins [J].
Barlowe, C .
JOURNAL OF CELL BIOLOGY, 1997, 139 (05) :1097-1108
[3]   GRASP65, a protein involved in the stacking of Golgi cisternae [J].
Barr, FA ;
Puype, M ;
Vandekerckhove, J ;
Warren, G .
CELL, 1997, 91 (02) :253-262
[4]   TRANSCYTOSIS-ASSOCIATED PROTEIN (TAP)/P115 IS A GENERAL FUSION FACTOR REQUIRED FOR BINDING OF VESICLES TO ACCEPTOR MEMBRANES [J].
BARROSO, M ;
NELSON, DS ;
SZTUL, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (02) :527-531
[5]   TRAPP stably associates with the Golgi and is required for vesicle docking [J].
Barrowman, J ;
Sacher, M ;
Ferro-Novick, S .
EMBO JOURNAL, 2000, 19 (05) :862-869
[6]   STRUCTURE AND TRANSCRIPTIONAL REGULATION OF THE GFAP GENE [J].
BRENNER, M .
BRAIN PATHOLOGY, 1994, 4 (03) :245-257
[7]   INTERACTIONS OF 3 DOMAINS DISTINGUISHING THE RAS-RELATED GTP-BINDING PROTEINS YPT1 AND SEC4 [J].
BRENNWALD, P ;
NOVICK, P .
NATURE, 1993, 362 (6420) :560-563
[8]   SYNTAXIN AND SYNAPTOBREVIN FUNCTION DOWNSTREAM OF VESICLE DOCKING IN DROSOPHILA [J].
BROADIE, K ;
PROKOP, A ;
BELLEN, HJ ;
OKANE, CJ ;
SCHULZE, KL ;
SWEENEY, ST .
NEURON, 1995, 15 (03) :663-673
[9]   Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins [J].
Cao, XC ;
Ballew, N ;
Barlowe, C .
EMBO JOURNAL, 1998, 17 (08) :2156-2165
[10]   Phosphatidylinositol-3-OH kinases are Rab5 effectors [J].
Christoforidis, S ;
Miaczynska, M ;
Ashman, K ;
Wilm, M ;
Zhao, LY ;
Yip, SC ;
Waterfield, MD ;
Backer, JM ;
Zerial, M .
NATURE CELL BIOLOGY, 1999, 1 (04) :249-252