Value of narrow band imaging in the early diagnosis of laryngeal cancer

被引:90
作者
Kraft, Marcel [1 ]
Fostiropoulos, Karolos [1 ]
Guertler, Nicolas [2 ]
Arnoux, Andre [3 ]
Davaris, Nikolaos [4 ]
Arens, Christoph [4 ]
机构
[1] Kantonsspital Baselland, Dept Otorhinolaryngol Head & Neck Surg, Liestal, Switzerland
[2] Univ Basel Hosp, Dept Otorhinolaryngol Head & Neck Surg, CH-4031 Basel, Switzerland
[3] Kantonsspital AG, Dept Otorhinolaryngol Head & Neck Surg, Aarau, Switzerland
[4] Univ Hosp Magdeburg, Dept Otorhinolaryngol Head & Neck Surg, Magdeburg, Germany
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2016年 / 38卷 / 01期
关键词
narrow band imaging; diagnostic imaging; larynx; vocal fold; laryngology; endoscopy; indirect laryngoscopy; dysplasia; cancer; HIGH-DEFINITION TELEVISION; ENDOSCOPIC EVALUATION; HEAD; CARCINOMA;
D O I
10.1002/hed.23838
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background. Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer. Methods. This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis. Results. In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods. Conclusion. NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions. (C) 2015 Wiley Periodicals, Inc.
引用
收藏
页码:15 / 20
页数:6
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