The first case of Anti-N-methyl-D-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report

被引：3

作者：

Cho, Eun Hye ^{[1
]}

Byun, Jung Mi ^{[1
,2
]}

Park, Ha Young ^{[3
]}

Kang, Mi Ri ^{[4
]}

Jung, Yoon Jung ^{[1
]}

Jeong, Chul Hoi ^{[5
]}

Kim, Young Nam ^{[1
,2
]}

Lee, Kyung Bok ^{[1
,2
]}

Sung, Moon Su ^{[1
,2
]}

Jeong, Dae Hoon ^{[1
,2
]}

机构：

[1] Inje Univ, Coll Med, Busan Paik Hosp, Dept Obstet & Gynecol, 75 Bokji Ro, Busan 473920, South Korea

[2] Inje Univ, Coll Med, Paik Inst Clin Res, Busan, South Korea

[3] Inje Univ, Busan Paik Hosp, Coll Med, Dept Pathol, Busan, South Korea

[4] Inje Univ, Busan Paik Hosp, Coll Med, Dept Neurol, Busan, South Korea

[5] Inje Univ, Haeundae Paik Hosp, Coll Med, Dept Obstet & Gynecol, Busan, South Korea

来源：

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2019年 / 58卷 / 04期

关键词：

Anti-NMDAR encephalitis; Ovarian tumor; Mucinous cystadenoma; TERATOMA;

D O I：

10.1016/j.tjog.2019.05.022

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune and paraneoplastic encephalitis caused by the N-methyl-D-aspartate receptor antibody which is related to tumors, such as teratomas of the ovaries. To our knowledge, this is the first reported case of Anti-NMDAR encephalitis associated with ovarian mucinous cystadenoma. Case report: A 23-year-old woman with a flu-like illness, confused mental status, and behavioral changes presented to the hospital. A right-sided ovarian tumor was detected during the work-up and was suspected to be a teratoma that might have caused the encephalitis. A laparoscopic right salpingo-oophorectomy (RSO) was performed. Histopathological examination revealed a mucinous cystadenoma. She recovered gradually and had complete resolution of symptoms after surgical removal of the mucinous cystadenoma and immunotherapy. Conclusion: Even though anti-NMDAR encephalitis is caused by ovarian teratoma because it contains various types of tissues, ovarian tumors in anti-NMDAR encephalitis may not be limited to ovarian teratomas. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

引用

页码：557 / 559

页数：3

共 8 条

[1] Treatment principles of ovarian teratoma with anti-N-methyl-D-aspartate receptor encephalitis [J].