Appropriateness of fresh-frozen plasma usage in hospital settings: a meta-analysis of the impact of organizational interventions

被引:18
作者
Damiani, Gianfranco [1 ]
Pinnarelli, Luigi
Sommella, Lorenzo
Farelli, Valentina
Mele, Luca
Menichella, Giacomo
Ricciardi, Walter
机构
[1] Univ Cattolica Sacro Cuore, Dept Publ Hlth, I-100168 Rome, Italy
关键词
QUALITY-ASSURANCE; TRANSFUSION PRACTICES; PROSPECTIVE AUDIT; OUTCOMES; IMPROVEMENT; GUIDELINES;
D O I
10.1111/j.1537-2995.2009.02371.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: Transfusions of fresh-frozen plasma (FFP) are a worldwide ever-growing practice. The most advanced health care organizations, to guarantee high-quality standards of interventions and safe procedures, should disseminate scientific evidence for promoting the appropriateness of transfusions and reducing avoidable risks. STUDY DESIGN AND METHODS: We carried out a systematic review of scientific literature searching for studies focused on the implementation of different strategy of organizational interventions aimed at improving clinicians' practice. RESULTS: Of 915 studies, 10 articles were included in our meta-analysis of risk of inappropriate transfusion after the implementation of an organizational intervention. The risk ratio of inappropriate transfusions before organizational interventions was 2.02 (95% confidence interval, 1.44-2.84) compared with after interventions. CONCLUSION: The organizational interventions showed a positive impact on the reduction of rates of inappropriate FFP transfusion episodes.
引用
收藏
页码:139 / 144
页数:6
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