Synthesis of new potentially biologically active pyranopyridones with tryptamine fragment

被引：2

作者：

Przhevalskii, N. M. ^{[1
]}

Laypanov, R. K. ^{[1
]}

Tokmakov, G. P. ^{[1
]}

Lukina, I., V ^{[1
]}

Vershinkin, D. A. ^{[1
]}

Tafeenko, V. A. ^{[2
]}

机构：

[1] Russian State Agr Univ, Moscow Timiryazev Agr Acad, 49 Ul Timiryazevskaya, Moscow 127434, Russia

[2] Lomonosov Moscow State Univ, Dept Chem, Build 3,1 Leninskie Gory, Moscow 119992, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2021年 / 70卷 / 03期

关键词：

aromatic aldehydes; biological activity; pyranopyridones; pyranopyridonotryptamines; multicomponent reactions; X-ray crystallography;

D O I：

10.1007/s11172-021-3124-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New pyranopyridonotryptamines 3 were synthesized by a three-component reaction of pyridonotryptamines 1, aromatic aldehydes 2, and malononitrile. The structures of compounds 3 were confirmed by X-ray crystallography. A series of compounds 3 underwent primary screening for the effect on the course of mitosis in seeds of plants of the species Allium cepa L.

引用

页码：555 / 561

页数：7

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