Asymptomatic colitis in naturally infected dogs with Leishmania infantum:: A prospective study

被引:37
作者
Adamama-Moraitou, Katerina K.
Rallis, Timoleon S.
Koytinas, Alexander F.
Tontis, Dimitris
Plevraki, Katerina
Kritsepi, Maria
机构
[1] Aristotle Univ Thessaloniki, Compan Anim Clin Med, Fac Vet Med, Thessaloniki 54627, Greece
[2] Univ Thessaly, Pathol Lab, Kardhitsa, Greece
[3] Aristotle Univ Thessaloniki, Clin Pathol Lab, Thessaloniki 54627, Greece
关键词
D O I
10.4269/ajtmh.2007.76.53
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A total of 31 dogs with naturally occurring and symptomatic leishmaniasis (Leishniania infantum), but without historical or clinical evidence of overt colitis, were included in this study. With owners' consent, a colonoscopy was performed in all these dogs, revealing patches of hyperemic, edematous, irregular, and mildly erosive colonic mucosa in 25.8% of the animals. Biopsies were obtained from the colonic mucosa and stained with hematoxylin-eosin (histopathology) and avidin-biotin-peroxidase technique (immunohistochemical detection of parasites). Leishniania amastigotes were detected immunohistochemically in 32.3% of the dogs. The most common inflammatory pattern in the colonic mucosa of these dogs was pyogranulomatous (90%), whereas in the dogs without Leishniania amastigotes immunohistochemically detected in the colonic mucosa (67.7%), there was no evidence of gross and microscopic lesions. Also, in 2 of the 10 dogs in which parasites were detected immunohistochemically in the colonic mucosa, no lesions could be detected on colonoscopy. There was no correlation between the dogs with or without parasites detected in the colonic mucosa regarding the sex, age, or the type of diet of these animals. However, the positive correlation (P < 0.001) found between colonic parasitism and gross lesions detected on colonoscopy would justify the inclusion of canine leishmaniasis in the list of differentials of canine chronic or recurrent colitis.
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页码:53 / 57
页数:5
相关论文
共 31 条
[1]   Canine leishmaniasis [J].
Alvar, J ;
Cañavate, C ;
Molina, R ;
Moreno, J ;
Nieto, J .
ADVANCES IN PARASITOLOGY, VOL 57, 2004, 57 :1-88
[2]  
Baneth G., 2006, INFECT DIS DOG CAT, P685
[3]   Atypical forms of canine leishmaniosis [J].
Blavier, A ;
Keroack, S ;
Denerolle, P ;
Goy-Thollot, I ;
Chabanne, L ;
Cadoré, JL ;
Bourdoiseau, G .
VETERINARY JOURNAL, 2001, 162 (02) :108-120
[4]   Immunohistochemical detection of Leishmania infantum in formalin-fixed, paraffin-embedded sections of canine skin and lymph nodes [J].
Bourdoiseau, G ;
Marchal, T ;
Magnol, JP .
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1997, 9 (04) :439-440
[5]  
BYUNGKI K, 1999, AM J GASTROENTEROL, V94, P3258
[6]   Acute haemorrhagic pancreatitis associated with canine visceral leishmaniasis [J].
Carrasco, L ;
deLara, FCM ;
Martin, E ;
Hervas, J ;
Molleda, JM ;
GomezVillamandos, JC ;
Lopez, R .
VETERINARY RECORD, 1997, 141 (20) :519-521
[7]   A retrospective clinical study of canine leishmaniasis in 150 dogs naturally infected by Leishmania infantum [J].
Ciaramella, P ;
Oliva, G ;
DeLuna, R ;
Gradoni, L ;
Ambrosio, R ;
Cortese, L ;
Scalone, A ;
Persechino, A .
VETERINARY RECORD, 1997, 141 (21) :539-543
[8]   Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis [J].
dos-Santos, WLC ;
David, J ;
Badaró, R ;
de-Freitas, LAR .
PARASITOLOGY RESEARCH, 2004, 92 (02) :89-94
[9]   LEISHMANIAL CHOLECYSTITIS AND COLITIS IN A PATIENT WITH VISCERAL LEISHMANIASIS [J].
FAHAL, AH ;
ELHAG, IA ;
ELHASSAN, AM ;
HASHIM, FA .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1995, 89 (03) :284-284
[10]   SKIN-LESIONS IN CANINE LEISHMANIASIS [J].
FERRER, L ;
RABANAL, R ;
FONDEVILA, D ;
RAMOS, JA ;
DOMINGO, M .
JOURNAL OF SMALL ANIMAL PRACTICE, 1988, 29 (06) :381-388