Efficient synthesis of new pyrano[2,3-d]pyrimidine-2,4-dione derivatives via a one-pot four-component reaction

被引：9

作者：

Irani, Sharmin ^{[1
]}

Maghsoodlou, Malek Taher ^{[1
]}

Hazeri, Nourallah ^{[1
]}

机构：

[1] Univ Sistan & Baluchestan, Dept Chem, Fac Sci, POB 98135-674, Zahedan, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2017年 / 14卷 / 06期

关键词：

4-Hydroxycoumarin; Four-component reaction; Pyrano[2,3-d]pyrimidine; CATALYZED 4+2 ANNULATIONS; DRUG DISCOVERY; MULTICOMPONENT REACTIONS; ORGANIC-SYNTHESIS; ANALOGS; DESIGN; CYCLIZATION; CHEMISTRY; 4H-PYRAN; PYRAZOLE;

D O I：

10.1007/s13738-017-1069-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper reports an efficient method for the synthesis of pyrano[2,3-d]pyrimidine derivatives via a one-pot four-component reaction between N,N-dimethyl barbituric acid, piperidine, aldehydes and 4-hydroxycoumarin. Mild reaction condition, easy purification and good yields are the main feature of this synthesis.

引用

页码：1189 / 1193

页数：5

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