Obsessive-compulsive Disorder: Diagnostic and Treatment Issues

被引:25
作者
Stein, Dan J. [1 ]
Denys, Damiaan [2 ,3 ]
Gloster, Andrew T. [4 ]
Hollander, Eric [5 ]
Leckman, James F. [6 ]
Rauch, Scott L. [7 ,8 ]
Phillips, Katharine A. [9 ]
机构
[1] Univ Cape Town, Dept Psychiat & Mental Hlth, ZA-7925 Cape Town, South Africa
[2] Univ Amsterdam, Acad Med Ctr, Dept Psychiat, NL-1105 AZ Amsterdam, Netherlands
[3] Royal Netherlands Acad Arts & Sci, Inst Neurosci, Amsterdam, Netherlands
[4] Tech Univ Dresden, Dept Psychol, Inst Clin Psychol & Pyschotherapy, Dresden, Germany
[5] Univ Hosp, Albert Einstein Coll Med, Montefiore Med Ctr, Dept Psychiat, Bronx, NY USA
[6] Yale Univ, Ctr Child Study, New Haven, CT 06520 USA
[7] Harvard Univ, Sch Med, Dept Psychiat, Belmont, MA 02178 USA
[8] McLean Hosp, Belmont, MA 02178 USA
[9] Brown Univ, Dept Psychiat & Human Behav, Providence, RI 02912 USA
关键词
Obsessive-compulsive disorder; Obsessive-compulsive spectrum; Diagnosis; Pharmacotherapy; Psychotherapy; Nosology; DSM-V; COGNITIVE-BEHAVIORAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; DEEP BRAIN-STIMULATION; GLUCOSE METABOLIC-RATE; SPECTRUM DISORDERS; SYMPTOM DIMENSIONS; ANXIETY DISORDERS; D-CYCLOSERINE; TOURETTES-SYNDROME; EXPOSURE THERAPY;
D O I
10.1016/j.psc.2009.05.007
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This article reviews current issues in the diagnosis and treatment of obsessive-compulsive disorder (OCD). The introduction of the selective serotonin reuptake inhibitors and of cognitive-behavioral therapy were significant advances for treating OCD. Nevertheless, there is a need to improve awareness of OCD and its management, and to develop novel approaches to treatment-refractory patients. Although the diagnostic criteria for OCD have remained unchanged for some time, there are several areas where potential modification may be useful. There is a growing evidence base on OCD symptom dimensions and subtyping, and it is timely to consider incorporating some of these emerging data into diagnostic classification systems.
引用
收藏
页码:665 / +
页数:22
相关论文
共 142 条
[71]   Obsessive-compulsive disorder with poor insight [J].
Matsunaga, H ;
Kiriike, N ;
Matsui, T ;
Oya, K ;
Iwasaki, Y ;
Koshimune, K ;
Miyata, A ;
Stein, DJ .
COMPREHENSIVE PSYCHIATRY, 2002, 43 (02) :150-157
[72]  
MCDOUGLE CJ, 1994, ARCH GEN PSYCHIAT, V51, P302
[73]   Cognitive versus behavior therapy in the group treatment of obsessive-compulsive disorder [J].
McLean, PD ;
Whittal, ML ;
Thordarson, DS ;
Taylor, S ;
Söchting, I ;
Koch, WJ ;
Paterson, R ;
Anderson, KW .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 2001, 69 (02) :205-214
[74]   Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited [J].
Menzies, Lara ;
Chamberlain, Samuel R. ;
Laird, Angela R. ;
Thelen, Sarah M. ;
Sahakian, Barbara J. ;
Bullmore, Ed T. .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2008, 32 (03) :525-549
[75]  
Meyer V., 1973, ISSUES TRENDS BEHAV
[76]   Obsessive-compulsive disorder phenotypes: implications for genetic studies [J].
Miguel, EC ;
Leckman, JF ;
Rauch, S ;
do Rosario-Campos, MC ;
Hounie, AG ;
Mercadante, MT ;
Chacon, P ;
Pauls, DL .
MOLECULAR PSYCHIATRY, 2005, 10 (03) :258-275
[77]   HMPAO SPET does not distinguish obsessive-compulsive and tic syndromes in families multiply affected with Gilles de la Tourette's syndrome [J].
Moriarty, J ;
Eapen, V ;
Costa, DC ;
Gacinovic, S ;
Trimble, M ;
Ell, PJ ;
Robertson, MM .
PSYCHOLOGICAL MEDICINE, 1997, 27 (03) :737-740
[78]   Inhibition of return in patients with obsessive-compulsive disorder [J].
Moritz, S ;
von Mühlenen, A .
JOURNAL OF ANXIETY DISORDERS, 2005, 19 (01) :117-126
[79]   A randomized controlled trial of Japanese patients with obsessive-compulsive disorder - Effectiveness of behavior therapy and fluvoxamine [J].
Nakatani, E ;
Nakagawa, A ;
Nakao, T ;
Yoshizato, C ;
Nabeyama, M ;
Kudo, A ;
Isomura, K ;
Kato, N ;
Yoshioka, K ;
Kawamoto, M .
PSYCHOTHERAPY AND PSYCHOSOMATICS, 2005, 74 (05) :269-276
[80]  
Nicolini H, 1998, Gac Med Mex, V134, P521