Recent Advances in Functionalization of Double Bond Based on Maleimides

被引：10
|
作者：
Yang, Zhenhua [1 ]
Zhu, Jianan [1 ]
Wen, Caiyue [1 ]
Ge, Yingxiang [1 ]
Zhao, Shengyin [1 ]
机构：
[1] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Minist Educ, Key Lab Sci & Technol Exotext, Shanghai 201620, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 39卷 / 09期
关键词：
maleimide; Michael addition; oxidative coupling; cycloaddition reaction; ENANTIOSELECTIVE CONJUGATE ADDITION; CATALYZED ASYMMETRIC 1,4-ADDITION; DIELS-ALDER REACTION; PHOSPHA-MICHAEL ADDITION; ARYL BORONIC ACIDS; C-H ACTIVATION; ARYLBORONIC ACIDS; EFFICIENT SYNTHESIS; ALKYLATION; NUCLEOPHILES;
D O I：
10.6023/cjoc201902012
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Maleimide, a common motif in a variety of natural alkaloids, has been extensively investigated due to its noteworthy biological activities and optical properties. Additionally, it can be transformed into many important heterocyclic frameworks such as succinimides, pyrrolidines, and 2-pyrrolidones. Thus, a great deal of attention has been focused on the development of new synthetic routes to access polyfunctionalized maleimides. In this article, the recent research progress in functionalization of double bond is reviewed based on maleimides according to Michael addition, oxidative coupling and cycloaddition reaction.
引用
收藏
页码：2412 / 2427
页数：16
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