(Diacetoxy)iodobenzene-Mediated Oxidative C-H Amination of Imidazopyridines at Ambient Temperature

被引：84

作者：

Mondal, Susmita ^{[1
]}

Samanta, Sadhanendu ^{[1
]}

Jana, Sourav ^{[1
]}

Hajra, Alakananda ^{[1
]}

机构：

[1] Visva Bharati, Dept Chem, Santini Ketan 731235, W Bengal, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 08期

关键词：

N BOND FORMATION; ONE-POT SYNTHESIS; METAL-FREE CONDITIONS; COUPLING REACTIONS; DIRECT ACCESS; FUNCTIONALIZATION; ARENES; IODINE; IMIDAZOHETEROCYCLES; BENZOXAZOLES;

D O I：

10.1021/acs.joc.7b00564

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Diacetoxy)iodobenzene (PIDA)-mediated direct oxidative C-H amination for the synthesis of 3-amino substituted imidazopyridines has been achieved under metal free conditions at room temperature in short reaction times. This methodology is also applicable for the regioselective amination of indolizines. Experimental results suggest that the reaction likely proceeds through a radical pathway.

引用

页码：4504 / 4510

页数：7

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