Life science research using positron annihilation spectroscopy: UV-irradiated mouse skin

被引：12
作者：
Jean, Y. C. [1 ]
Chen, Hongmin
Liu, Guang
Gadzia, Joseph E.
机构：
[1] Univ Missouri, Dept Chem, Kansas City, MO 64110 USA
[2] Univ Kansas, Med Ctr, Dept Internal Med, Kansas City, KS 66103 USA
[3] Kansas Med Clin, Topeka, KS 66614 USA
来源：
RADIATION PHYSICS AND CHEMISTRY | 2007年 / 76卷 / 02期
基金：
美国国家科学基金会;
关键词：
life science; mouse skin; degradation; positron annihilation; UV irradiation;
D O I：
10.1016/j.radphyschem.2006.03.008
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Positron annihilation spectroscopy (PAS) is applied to study mouse skin under different UV irradiations as a function of positron incident energy (0-30 keV). Significant variations in the depth profile of S parameter are observed in a period of hours and of days for UVA and UVB exposures, respectively. The high sensitivity of positron annihilation signals responding to UV irradiation shows that PAS may be developed as a new noninvasive technique for the detection of molecular damage in life science research. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：70 / 75
页数：6
相关论文
共 25 条
[1]   Activation of expression of hedgehog target genes in basal cell carcinomas [J].
Bonifas, JM ;
Pennypacker, S ;
Chuang, PT ;
McMahon, AP ;
Williams, M ;
Rosenthal, A ;
de Sauvage, FJ ;
Epstein, EH .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2001, 116 (05) :739-742
[2]   POSITRON DYNAMICS IN SOLIDS [J].
BRANDT, W .
APPLIED PHYSICS, 1974, 5 (01) :1-23
[3]   Free-volume hole model for positronium formation in polymers: surface studies [J].
Cao, H ;
Zhang, R ;
Yuan, JP ;
Huang, CM ;
Jean, YC ;
Suzuki, R ;
Ohdaira, T ;
Nielsen, B .
JOURNAL OF PHYSICS-CONDENSED MATTER, 1998, 10 (46) :10429-10442
[4]   Degradation of polymer coating systems studied by positron annihilation spectroscopy. 3. Wavelength dependence of UV irradiation effect [J].
Cao, H ;
Yuan, JP ;
Zhang, R ;
Huang, CM ;
He, Y ;
Sandreczki, TC ;
Jean, YC ;
Nielsen, B ;
Suzuki, R ;
Ohdaira, T .
MACROMOLECULES, 1999, 32 (18) :5925-5933
[5]  
Cao H, 1999, J POLYM SCI POL PHYS, V37, P1289, DOI 10.1002/(SICI)1099-0488(19990615)37:12<1289::AID-POLB9>3.3.CO
[6]  
2-G
[7]   Degradation of polymer coating systems studied by positron annihilation spectroscopy. 1. UV irradiation effect [J].
Cao, H ;
Zhang, RW ;
Sundar, CS ;
Yuan, JP ;
He, Y ;
Sandreczki, TC ;
Jean, YC ;
Nielsen, B .
MACROMOLECULES, 1998, 31 (19) :6627-6635
[8]   Durability and free volume in polymeric coatings studied by positron annihilation spectroscopy [J].
Chen, H ;
Zhang, R ;
Li, Y ;
Zhang, JJ ;
Wu, YC ;
Sandreczki, TC ;
Mallon, PE ;
Suzuki, R ;
Ohdaira, T ;
Gu, X ;
Nguyen, T ;
Jean, YC .
POSITRON ANNIHILATION, ICPA-13, PROCEEDINGS, 2004, 445-6 :274-276
[9]  
Coleman P. G., 2000, POSITRON BEAMS THEIR
[10]  
Dupasquier A., 1995, Positron spectroscopy of solids"
123